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Keywords: Craniofacial development
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Journal Articles
Journal: Development
Development (2020) 147 (24): dev192948.
Published: 24 December 2020
...Fangfang Yan; Peilin Jia; Hiroki Yoshioka; Akiko Suzuki; Junichi Iwata; Zhongming Zhao ABSTRACT Craniofacial development is regulated through dynamic and complex mechanisms that involve various signaling cascades and gene regulations. Disruption of such regulations can result in craniofacial birth...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (23): dev189076.
Published: 14 December 2020
...Martha L. Echevarría-Andino; Benjamin L. Allen ABSTRACT The Hedgehog (HH) pathway controls multiple aspects of craniofacial development. HH ligands signal through the canonical receptor PTCH1, and three co-receptors: GAS1, CDON and BOC. Together, these co-receptors are required during embryogenesis...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (18): dev191213.
Published: 21 September 2020
... both normal and disordered craniofacial development in FaceBase, all freely available to the research community on the FaceBase Hub website. The Hub has developed numerous visualization and analysis tools designed to promote integration of multidisciplinary data while remaining dedicated to the FAIR...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (15): dev170241.
Published: 02 August 2019
... the development of Scx + /Sox9 + cells. FGF Notch Craniofacial development Enthesis Perichondrium Tendon Mouse Body movement requires tendons to deliver high tensile forces from skeletal muscle to bone. As tendon and bone have vastly different physical properties, a transitional...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (14): dev175042.
Published: 24 July 2019
... craniofacial development, but the molecular role of MOZ in this context is unclear. Using genetic interaction and genomic studies, we have investigated the effects of loss of MOZ on the gene expression program during mouse development. Among the more than 500 genes differentially expressed after loss of MOZ...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (14): dev164780.
Published: 26 July 2018
....2004.08.007 Minoux , M. and Rijli , F. M. ( 2010 ). Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development . Development   137 , 2605 - 2621 . 10.1242/dev.040048 Miyashita , T. ( 2016 ). Fishing for jaws in early vertebrate...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (14): 2677–2688.
Published: 15 July 2016
... , M. , Cox , T. C. , Cunningham , M. J. , Detwiler , L. T. , Heike , C. L. , Hochheiser , H. , Mejino , J. L. V. , Travilian , R. S. , et al. ( 2013 ). The ontology of craniofacial development and malformation for translational craniofacial research . Am. J. Med...
Journal Articles
Journal: Development
Development (2016) 143 (3): 504–515.
Published: 01 February 2016
... . 10.1242/dev.01419 Cordero , D. R. , Brugmann , S. , Chu , Y. , Bajpai , R. , Jame , M. and Helms , J. A. ( 2011 ). Cranial neural crest cells on the move: their roles in craniofacial development . Am. J. Med. Genet. A   155 , 270 - 279 . 10.1002/ajmg.a.33702...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (16): 2775–2780.
Published: 15 August 2015
... Verzi , M. P. , Agarwal , P. , Brown , C. , McCulley , D. J. , Schwarz , J. J. and Black , B. L. ( 2007 ). The transcription factor MEF2C is required for craniofacial development . Dev. Cell   12 , 645 - 652 . 10.1016/j.devcel.2007.03.007 Vong , L. H. , Ragusa...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (7): 1357–1367.
Published: 01 April 2015
...-mediated apoptosis through SMAD1/5 phosphorylation and MDM2-p53 complex formation in cranial neural crest cells, regulating nasal cartilage morphogenesis. BMP SMAD Craniofacial development Neural crest cell p53 MDM2 Apoptosis Nasal septum Nasal portions of each embryo were lysed in RIPA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (3): 567–574.
Published: 01 February 2015
... ectodermal zone BMP SHH Cleft lip and palate Craniofacial development Facial fusion Chick Mouse Morphogenesis of the face is a complex process that involves iterative signaling between epithelial and mesenchymal cells. These interactions establish domains of directional growth that ultimately...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 3050–3061.
Published: 01 August 2014
... craniofacial development and embryonic survival, altering Hand1 phosphoregulation, and consequently Hand1 dimerization affinities, in NCCs results in severe mid-facial clefting and neonatal death. Hand1 phosphorylation mutants exhibit a non-cell-autonomous increase in pharyngeal arch cell death accompanied by...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (21): 4386–4397.
Published: 01 November 2013
... selectively downregulates Bmp5 , although not paired related homeobox 1 ( Prrx1 ), which encodes a transcription factor involved in craniofacial development ( Martin et al., 1995 ) ( Fig. 4I,J,Q,R ). We next analysed Bmp4 expression. At E12.0-12.5, Bmp4 is expressed at the distal edge (tip) of the...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (16): 3413–3422.
Published: 15 August 2013
... responses. Genetic inactivation of the genes encoding the LAR family receptor protein tyrosine phosphatases RPTP-σ and LAR revealed their functional redundancy in craniofacial development. Double-mutant embryos exhibit a shorter lower jaw (micrognathia), accompanied by a failure in tongue development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (9): 1827–1838.
Published: 01 May 2011
... ). RT-PCR analysis revealed a slight reduction in the CNC markers SOX10, PAX7, SNAIL2 and TWIST in Nutlin-3-treated neural tubes versus those of control (DMSO-treated) embryos ( Fig. 4J ). Next, we explored the long-term consequences of a reduction in SNAIL2 and ETS1 for craniofacial development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (6): 933–942.
Published: 15 March 2009
... its DNA-binding activity. The embryonic lethality of Hand2 EDE/EDE mutant mice precluded analysis of the potential requirement of Hand2 DNA binding in later phases of development in these embryos. To test whether DNA-binding activity was required for later steps in craniofacial development...
Journal Articles
Journal: Development
Development (2008) 135 (22): 3775–3787.
Published: 15 November 2008
... Retinoic acid Bmp2 Cartilage Bone Chondrocyte Osteoblast Osteopontin Osterix Craniofacial development Vertebra Zebrafish Skeletal development is highly conserved in vertebrates and involves two main processes: skeletal patterning to define the shape and location of the different skeletal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (17): 2981–2991.
Published: 01 September 2008
... ( Alk3 ) Vasculogenesis Heart development Craniofacial development Matrix metalloproteinase (metallopeptidase) MMP2 MMP9 Smooth muscle cell proliferation Pericyte apoptosis SM22α (transgelin, Tagln) Mouse Bone morphogenetic protein receptors (BMPRs) are members of the transforming...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (11): 1935–1946.
Published: 01 June 2008
... Bromodomain PWWP domain Moz Hox gene expression Craniofacial development Cranial neural crest Pharyngeal arch Anterior-posterior patterning Homeotic transformation Zebrafish Anterior-posterior patterning of the vertebrate head, including segmental identity determination of the seven...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3437–3448.
Published: 01 October 2007
...Karine Rizzoti; Robin Lovell-Badge Craniofacial development is a complex multi-step process leading to the morphogenesis of the face and sense organs, and to that of the neck, including the anteriormost part of the respiratory and digestive apparatus and associated endocrine glands. In vertebrates...