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Keywords: Craniofacial
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Journal Articles
Journal: Development
Development (2021) 148 (9): dev193755.
Published: 07 May 2021
... signalling pathway genes during chicken craniofacial development . Dev. Dyn. 238 , 1150 - 1165 . 10.1002/dvdy.21934 Geetha-Loganathan , P. , Nimmagadda , S. , Fu , K. and Richman , J. M. ( 2014 ). Avian facial morphogenesis is regulated by c-Jun N-terminal kinase/planar cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (18): dev188631.
Published: 12 March 2021
... comparison (morphometrics) traditionally uses manually located landmarks and is limited by landmark number and operator accuracy. Here, we apply a landmark-free method to characterise the craniofacial skeletal phenotype of the Dp1Tyb mouse model of Down syndrome and a population of the Diversity Outbred (DO...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (24): dev194498.
Published: 23 December 2020
... mutant. IRF6 ESRP1 Craniofacial Cleft Development Development of vertebrate craniofacial structures requires coordinated cellular induction, migration, proliferation and differentiation, which allow for the positioning of adjacent epithelial-lined facial processes that ultimately...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev187997.
Published: 17 July 2020
...Karl B. Shpargel; Cassidy L. Mangini; Guojia Xie; Kai Ge; Terry Magnuson; Sally Dunwoodie; John Wallingford ABSTRACT Kabuki syndrome (KS) is a congenital craniofacial disorder resulting from mutations in the KMT2D histone methylase (KS1) or the UTX histone demethylase (KS2). With small cohorts...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (11): dev190488.
Published: 11 June 2020
...Ceilidh Marchant; Peter Anderson; Quenten Schwarz; Sophie Wiszniak ABSTRACT Craniofacial development is a complex morphogenic process that requires highly orchestrated interactions between multiple cell types. Blood vessel-derived angiocrine factors are known to promote proliferation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (14): dev175893.
Published: 22 July 2019
...-metamorphic Xenopus laevis tadpoles to self-correct malformed craniofacial tissues. We found that tadpoles can adaptively improve and normalize abnormal craniofacial morphology caused by numerous developmental perturbations. We then investigated the tissue-level and molecular mechanisms that mediate the self...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (12): dev165498.
Published: 26 June 2018
.... Funding This work was funded by the National Institute of Dental and Craniofacial Research (R01-DE018405 and R35-DE027550 to J.G.C.). Deposited in PMC for release after 12 months. References Akimenko , M. A. , Ekker , M. , Wegner , J. , Lin , W. and Westerfield , M...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (16): 2994–3005.
Published: 15 August 2017
... for craniofacial development, how genetic programs drive this regionalization remains incompletely understood. Here we use combinatorial labeling of zebrafish cranial neural crest-derived cells (CNCCs) to define global gene expression along the dorsoventral axis of the developing arches. Intersection of region...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (11): 2021–2031.
Published: 01 June 2017
.... Endothelin Craniofacial Neural crest cell Hinge and caps Knockout mouse Development of the vertebrate face requires the coordinated regulation of patterning cues throughout the pharyngeal arches of the developing embryo. Populated by cranial neural crest cells (NCCs) originating in the dorsal...
Journal Articles
Journal: Development
Development (2016) 143 (13): 2344–2355.
Published: 01 July 2016
....); and by grants from the National Institutes of Health National Institute of Dental and Craniofacial Research [R03DE023864 to Y.L., R01DE013681 to R.J.]. Deposited in PMC for release after 12 months. References Abbott , B. D. ( 2000 ). Palatal dysmorphogenesis. Palate organ culture . Methods Mol...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (6): 1089–1094.
Published: 15 March 2015
... sequences. Fluorescent images were acquired on a Zeiss LSM5 confocal microscope. Dissected craniofacial cartilages were photographed on a Leica DM2500 upright microscope. To quantitate pouch defects, misshapen or normal pouches were scored as 1 and missing pouches as 0. For cartilage defects, normal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 3003–3012.
Published: 01 August 2014
.... Although phenotypically similar to talpid 3 , talpid 2 has a distinct facial phenotype and an unknown cellular, molecular and genetic basis. We set out to determine the etiology of the craniofacial phenotype of this mutant. We confirmed that primary cilia were disrupted in talpid 2 mutants. Molecularly, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2035–2045.
Published: 15 May 2014
... craniofacial tendon and ligament progenitors are neural crest derived, as in mammals. Cranial and fin tendon progenitors can be induced in the absence of differentiated muscle or cartilage, although neighboring muscle and cartilage are required for tendon cell maintenance and organization, respectively...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 76–81.
Published: 01 January 2013
... of Biologists Ltd Palate irf6 wnt9a Cranial neural crest Craniofacial Zebrafish Palate development provides an excellent example of conservation of genetic programs and morphogenesis events across vertebrate ontogeny. Five distinct facial prominences converge to shape...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (15): 2804–2813.
Published: 01 August 2012
... of the visceral organs and craniofacial skeleton . Dev. Biol. 283 , 310 - 321 . Alexander C. , Zuniga E. , Blitz I. L. , Wada N. , Le Pabic P. , Javidan Y. , Zhang T. , Cho K. W. , Crump J. G. , Schilling T. F. ( 2011 ). Combinatorial roles for BMPs...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (5): 958–967.
Published: 01 March 2012
...Natalia Moncaut; Joe W. Cross; Christine Siligan; Annette Keith; Kevin Taylor; Peter W. J. Rigby; Jaime J. Carvajal The specification of the skeletal muscle lineage during craniofacial development is dependent on the activity of MYF5 and MYOD, two members of the myogenic regulatory factor family...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5135–5146.
Published: 01 December 2011
...Courtney Alexander; Elizabeth Zuniga; Ira L. Blitz; Naoyuki Wada; Pierre Le Pabic; Yashar Javidan; Tailin Zhang; Ken W. Cho; J. Gage Crump; Thomas F. Schilling Bone morphogenetic proteins (BMPs) play crucial roles in craniofacial development but little is known about their interactions with other...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (23): 5147–5156.
Published: 01 December 2011
... exclusion of grem2 expression is crucial for development of the ventral and intermediate facial skeleton. Based on our findings, we propose a network model of craniofacial patterning in which positive and negative feedback progressively creates two states of BMP signaling: high BMP activity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (11): 2249–2259.
Published: 01 June 2011
... and Dlx6 in the distal mandibular arch. Although a ‘Dlx code’ appears to establish the proximal-distal identity of the mandibular arch during craniofacial development (for a review, see Depew and Simpson, 2006 ), the mechanism by which they act remains only partially elucidated. Here, we have...
Journal Articles
Journal: Development
Development (2010) 137 (23): 3973–3984.
Published: 01 December 2010
... and dermal cell identity in the cranium. The absence of the Wnt signaling cue leads to formation of cartilage in craniofacial and ventral trunk regions at the expense of dermal and bone lineages. Dermo1 can be a direct transcription target and may mediate the functional role of Wnt signaling in dermal...
Includes: Supplementary data