... reveal mechanistic differences between the early expansive and later neurogenic periods of cortical development. Corticogenesis Mitosis MADM Neurogenesis Sp2 Neural stem cell Formation of the cerebral cortex begins in the neuroepithelium of the dorsal telencephalon and culminates...

... forebrain development. Cux2 Lmx1a Cortical hem Corticogenesis Enhancer Telencephalon Children's Hospital Colorado 10.13039/100007180 Boettcher Foundation 10.13039/100005508 During forebrain development, neural progenitor cells give rise to many different types...

... to a marked expansion of a distinct proliferative cell population, basal to the SVZ. These cells constitute a novel neurogenic cell layer, similar to the OSVZ, and contribute to corticogenesis by heading for deeper cortical layers as a part of the cortical plate. * Author for correspondence...

... of radial glial cells (RGC) and intermediate precursors (IPC) was increased, expanding both populations, with greater effect on IPCs. Furthermore, cell cycle re-entry was increased during early corticogenesis, whereas cell cycle exit was augmented at middle stage. Consequently, neurogenesis was reduced...

...Keisuke Watanabe; Hirohide Takebayashi; Asim K. Bepari; Shigeyuki Esumi; Yuchio Yanagawa; Nobuaki Tamamaki During corticogenesis, the regulation of neuronal migration is crucial for the functional organization of the neocortex. Glutamatergic neurons are major excitatory components of the mammalian...

... Institute, National Cancer Center, Goyang 410-769, Republic of Korea Competing interests statement 22 3 2010 © 2010. Corticogenesis Neurogenesis Zinc finger genes Fezf1 Fezf2 Hes5 neurogenin 2 Mouse The mammalian forebrain is the most complex...

...Hilary A. North; Xiumei Zhao; Sharon M. Kolk; Meredith A. Clifford; Daniela M. Ziskind; Maria J. Donoghue Eph receptors are widely expressed during cerebral cortical development,yet a role for Eph signaling in the generation of cells during corticogenesis has not been shown. Cortical progenitor...

... and endows them with neurogenic properties. Using a Cre/ loxP -based approach, we studied the effect of conditional activation of two Pax6 isoforms, Pax6 and Pax6-5a ,on the corticogenesis of transgenic mice. We found that activation of either Pax6 or Pax6-5a inhibits progenitor proliferation...

.... *Author for correspondence (e-mail: [email protected] ) 8 3 2001 © 2001. 2001 Cell migration Cortical plate Corticogenesis Differentiation Neocortex Otx1 Pax6 Small eye mutant Subventricular zone The cerebral cortex of the mammalian brain consists of six...