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Keywords: Computational biology
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Journal Articles
Journal: Development
Development (2017) 144 (19): 3465–3474.
Published: 1 October 2017
... disease mechanism and developing new therapeutic strategies ( Lie et al., 2004 ; Lazarov et al., 2010 ). Notch signaling Id transcription factors Neural stem cells Neurogenesis Computational biology Summary: Computational analysis of transcriptome data from neural stem cells reveals...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (1): 17–32.
Published: 1 January 2017
... sequencing has been used to study developmental and stem cell biology, providing insights into cell type diversity and developmental dynamics. RNA-Seq Computational biology Gene regulatory networks Pseudotime Single cell Stem cells To characterize the diversity of cell types...
Journal Articles
Journal: Development
Development (2016) 143 (22): 4097–4100.
Published: 15 November 2016
... Stem Cell Symposium this year. Bioinformatics Computational biology Epigenetics Genome editing Stem cells Transcription Cancer Research UK 10.13039/501100000289 A19778 Quantitative approaches have been boosted across many areas of biology by the relentless improvements...
Journal Articles
Journal: Development
Development (2015) 142 (13): 2250–2260.
Published: 1 July 2015
... of Biologists Ltd 2015 Summary: This Review discusses the principles, applications and limitations of different computational strategies used to study the mechanisms underlying pluripotency regulation in embryonic stem cells. Computational biology Embryonic stem cells Multi-scale models Network...
Journal Articles
Journal: Development
Development (2014) 141 (23): 4526–4536.
Published: 1 December 2014
... et al., 2012 ). Branching morphogenesis Image-based modeling Turing pattern Computational biology © 2014. Published by The Company of Biologists Ltd 2014 3 8 2014 10 9 2014 Competing interests The authors declare no competing financial interests. * Author...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (22): 4867–4874.
Published: 15 November 2011
... interests statement The authors declare no competing financial interests. 11 9 2011 © 2011. Dorsal gradient Drosophila embryo Computational biology Confidence interval Morphogen gradient Statistics In one of the most widely studied tissue patterning...
Journal Articles
Journal: Development
Development (2004) 131 (12): 2887–2897.
Published: 15 June 2004
... and found to be reduced in the presence of an αvβ3 integrin inhibitor. These dynamic cell motility data result in new hypotheses regarding primordial endothelial cell behavior during embryonic vasculogenesis. Vasculogenesis Endothelial cells αvβ3 integrin Time-lapse Computational biology Quail...
Includes: Multimedia, Supplementary data