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Keywords: Compound mutants
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Journal Articles
Bénédicte Mascrez, Manuel Mark, Andrée Dierich, Norbert B. Ghyselinck, Philippe Kastner, Pierre Chambon
Journal:
Development
Development (1998) 125 (23): 4691–4707.
Published: 1 December 1998
... a subset of the abnormalities previously observed in RXRα −/− mutants, often with incomplete penetrance. In marked contrast, RXRα af2 o /RXRβ −/− and RXRα af2 o /RXRβ −/− /RXRγ −/− compound mutants display a large array of malformations, which nearly recapitulate the full spectrum of the defects...