..., and together they form the adult neuropil-glia architecture. Both lineages require the FGF receptor Heartless to proliferate, and the homeoprotein Prospero to differentiate into ALG. Lineage-specific inhibition of gliogenesis revealed that each lineage compensates for deficiency in the proliferation...

...Kensuke Kawade; Gorou Horiguchi; Hirokazu Tsukaya The way in which the number and size of cells in an organ are determined poses a central challenge in our understanding of organ size control. Compensation is an unresolved phenomenon, whereby a decrease in cell proliferation below some threshold...

.... Unexpectedly, endothelial-specific knockout of integrin α5 has no obvious effect on developmental angiogenesis. We provide evidence for genetic interaction between mutations in integrin α5 and αv and for overlapping functions and compensation between these integrins and perhaps others. Nonetheless, in embryos...

... et al., 1991 ; King and Bryant, 1982 ). The main limitation of these studies was the need for physical manipulation of individual embryos, which prevented the molecular analysis of the repair process. Cyclin E Cell proliferation Programmed cell death Apoptosis Compensation Drosophila...

... and must be considered as first authors 23 01 1997 © 1997 by Company of Biologists 1997 cell death compensation Drosophila pattern repair bicoid Establishment and maintenance of proper proportions and pattern are of paramount importance in animal development. A great...