...Rodrigue Peraldi; Marie Kmita ABSTRACT Animal body plans are established during embryonic development by the Hox genes. This patterning process relies on the differential expression of Hox genes along the head-to-tail axis. Hox spatial collinearity refers to the relationship between...

...Patrick Tschopp; Alix J. Christen; Denis Duboule The importance of Hox genes in the specification of neuronal fates in the spinal cord has long been recognized. However, the transcriptional controls underlying their collinear expression domains remain largely unknown. Here we show in mice...

...-regulatory modules Collinearity Motif discovery Medaka Synexpression Tissue determination during embryogenesis is governed by dynamic developmental gene expression, and failures of proper gene expression in time and space lead to embryonic defects. Spatiotemporal gene expression...