... unknown, especially in the kidney and the mammary gland. Collective migration Morphodynamics Morphogen gradients Mechanical stress Smooth muscle Summary: This Development at a Glance article highlights the conserved and divergent mechanisms that are used to construct branched tissues...

... reveal an unexpected link between the initiation of collective migration and sequential formation of protoneuromasts in the primordium. * Author for correspondence ( [email protected] ) Competing interests The authors declare no competing or financial interests. 12 12 2017 13...

...Martina Nagel; Rudolf Winklbauer ABSTRACT The leading-edge mesendoderm (LEM) of the Xenopus gastrula moves as an aggregate by collective migration. However, LEM cells on fibronectin in vitro show contact inhibition of locomotion by quickly retracting lamellipodia upon mutual contact. We found...

... ( [email protected] ; [email protected] ) Competing interests The authors declare no competing or financial interests. © 2016. Published by The Company of Biologists Ltd 2016 Summary: This Hypothesis article poses that EMT and collective migration can be viewed as extreme cases...

...Damian Dalle Nogare; Katherine Somers; Swetha Rao; Miho Matsuda; Michal Reichman-Fried; Erez Raz; Ajay B. Chitnis Collective migration of cells in the zebrafish posterior lateral line primordium (PLLp) along a path defined by Cxcl12a expression depends on Cxcr4b receptors in leading cells...

... at the edge of the tissue guide trailing ‘followers’ that become assembled into polarised epithelial tissues en route. Here, we combine quantitative imaging and perturbation approaches to investigate epithelial cell state transitions during collective migration and organogenesis, using the zebrafish lateral...

.... Consecutively, the CCV becomes extended by active migration of the ECs located underneath the epidermis towards the ECs of the heart inflow tract. Our results show that Cdh5 is uniquely required for the directionality of the collectively migrating ECs in the CCV. To enclose the lumen, ECs at the edges...

... ) Competing interests statement The authors declare no competing financial interests. 25 2 2013 © 2013. Published by The Company of Biologists Ltd 2013 ADAMTS Collective migration Drosophila GON-1 Salivary gland Cell migration is crucial to shaping...

...Virginie Lecaudey; Gulcin Cakan-Akdogan; William H. J. Norton; Darren Gilmour The collective migration of cells in the form of cohesive tissues is a hallmark of both morphogenesis and repair. The extrinsic cues that direct these complex migrations usually act by regulating the dynamics...