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Keywords: Collagen IV
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Journal Articles
Journal: Development
Development (2020) 147 (16): dev185140.
Published: 24 August 2020
... in transient hypervascularization but delays BBB maturation in specific CNS regions, as evidenced by both upregulation of Plvap and increased tracer leakage across the neurovasculature due to reduced Wnt/β-catenin activity. In addition, collagen IV deposition in the vascular basement membrane is reduced...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (17): 3102–3113.
Published: 01 September 2017
... to CNS structure. Expressed and active in surface glia, AdamTS-A acts in parallel to perlecan and in opposition to viking / collagen IV and βPS - integrin to keep CNS lineages rooted in place and to preserve the structural integrity of the CNS. viking / collagen IV and βPS - integrin are known to promote...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (9): 1433–1442.
Published: 01 May 2009
...-terminal Kunitz-type serine proteinase inhibitory domains. We show that mutations affecting MIG-6L specifically and cell-autonomously decrease the rate of post-embryonic DTC migration, mimicking a post-embryonic collagen IV deficit. We also show that MIG-6S has two separable functions - one...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (13): 3069–3077.
Published: 01 July 2005
... polar cells undergo an unusual and asymmetrical apical capping with major basement membrane proteins, including the two Drosophila Collagen IV α chains, Laminin A and Perlecan. Capping of polar cells proceeds through a novel, basal-to-apical transcytosis mechanism that involves the small GTPase Drab5...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (7): 1619–1628.
Published: 01 April 2004
... for cellular interactions. The network of collagen IV is thought to define the scaffold integrating other components such as, laminins, nidogens or perlecan, into highly organized supramolecular architectures. To analyze the functional roles of the major collagen IV isoform α1(IV) 2 α2(IV) for basement...