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Keywords: Cloaca
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Journal Articles
Journal: Development
Development (2023) 150 (14): dev201630.
Published: 13 July 2023
... neural tube closure, genitourinary tract and hindgut defects. We show that, in Tmem132a mutant embryos, visceral endoderm fails to be excluded from the medial region of early hindgut, leading directly to the loss or malformation of cloaca-derived genitourinary and gastrointestinal structures...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (23): 3949–3957.
Published: 1 December 2009
...Ashley W. Seifert; Cortney M. Bouldin; Kyung-Suk Choi; Brian D. Harfe; Martin J. Cohn Malformations of the external genitalia are among the most common congenital anomalies in humans. The urogenital and anorectal sinuses develop from the embryonic cloaca, and the penis and clitoris develop from...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (23): 3959–3967.
Published: 1 December 2009
... a central role in GT development by simultaneously regulating patterning of the cloacal field and supporting an outgrowth signal. * Author for correspondence ( lima@dom.wustl.edu ) 24 9 2009 © 2009. 2009 Shh Genital tubercle Cloaca Hox Mouse External genitalia (the penis...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (3): 525–533.
Published: 1 February 2007
... suggest that the cloaca, and its derivative, the urogenital sinus, contribute to the formation of these organs. However, it is unknown how the primary tissue lineages in, and adjacent to, the cloaca give rise to the above organs, nor is bladder formation understood. While it is known that sonic hedgehog...
Journal Articles
Journal: Development
Development (2006) 133 (11): 2275–2284.
Published: 1 June 2006
... required for development of the cloaca (the common gut and urogenital opening). Using a novel assay for cloacal function, we find that larvae with reduced mid-gastrula Bmp signaling cannot properly excrete waste. We show that the cloacal defects result from alterations in the morphogenesis of the cloaca...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (3): 447–458.
Published: 1 February 2005
...Petr Valasek; Darrell J. R. Evans; Flavio Maina; Milos Grim; Ketan Patel The cloaca serves as a common opening to the urinary and digestive systems. In most mammals, the cloaca is present only during embryogenesis, after which it undergoes a series of septation events leading to the formation...