... deficiency on lip development is currently unknown. Multiple lines of evidence have shown that episodes of embryonic hypoxia during the first trimester of human pregnancy are associated with developmental defects and craniofacial malformations, including cleft lip and palate (reviewed by Webster...

... BMP SHH Cleft lip and palate Craniofacial development Facial fusion Chick Mouse Morphogenesis of the face is a complex process that involves iterative signaling between epithelial and mesenchymal cells. These interactions establish domains of directional growth that ultimately sculpt...