...Tengyang Qiu; Barbora Hutečková; Maisa Seppala; Martyn T. Cobourne; Zhi Chen; Mária Hovořáková; Marcela Buchtová; Abigail S. Tucker ABSTRACT The vestibular lamina (VL) forms the oral vestibule, creating a gap between the teeth, lips and cheeks. In a number of ciliopathies, formation...

..., distribution and reproduction in any medium provided that the original work is properly attributed. Summary: ARL13B, a protein enriched in a signaling hub (cilia), is required for the maturation of neurons in the mouse nose and its loss impairs smell. ARL13B Maturation Ciliopathies Primary...

...Christian Louis Bonatto Paese; Evan C. Brooks; Megan Aarnio-Peterson; Samantha A. Brugmann ABSTRACT Ciliopathies represent a growing class of diseases caused by defects in microtubule-based organelles called primary cilia. Approximately 30% of ciliopathies are characterized by craniofacial...

.... As such, ciliary defects produce a spectrum of human diseases, termed ciliopathies, and deregulation of this important organelle also plays key roles during tumor formation and progression. Recent studies have begun to clarify the key mechanisms that regulate ciliary assembly and disassembly in both normal...

...Sharda Prasad Yadav; Neel Kamal Sharma; Chunqiao Liu; Lijin Dong; Tiansen Li; Anand Swaroop ABSTRACT Defects in cilia centrosomal genes cause pleiotropic clinical phenotypes, collectively called ciliopathies. Cilia biogenesis is initiated by the interaction of positive and negative regulators...

.../licenses/by/3.0 ), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Primary cilia Craniofacial talpid 2 Gli processing Hedgehog signaling Ciliopathies Chicken The chick is a classic embryological...

... ciliogenesis and Hh signalling. † Author for correspondence (e-mail: cat24@bath.ac.uk ) * These authors contributed equally to this work 11 12 2008 © 2009. 2009 Primary cilia Centrosome Hedgehog signalling Ciliopathies Talpid3 Chicken Neural tube Embryo...