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Keywords: Ci
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Journal Articles
Journal: Development
Development (2011) 138 (19): 4219–4231.
Published: 01 October 2011
... activate the Hh pathway. Interestingly, we observe that graded Hh signals progressively increase Fu kinase domain dimerization and AL phosphorylation, suggesting that Hh activates Fu in a dose-dependent manner. Moreover, we find that activated Fu regulates Cubitus interruptus (Ci) by both promoting its...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (15): 3125–3134.
Published: 01 August 2011
... wing results from the communication between a previously defined ME and a nearby cis-regulatory element termed the C enhancer. The C enhancer integrates the activities of the Notch and Hedgehog signalling pathways and, from the early wing primordium stage, drives expression to a thin stripe...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (12): 2533–2542.
Published: 15 June 2011
...Steven A. Marks; Daniel Kalderon Hedgehog (Hh) signaling activates full-length Ci/Gli family transcription factors and prevents Ci/Gli proteolytic processing to repressor forms. In the absence of Hh, Ci/Gli processing is initiated by direct Pka phosphorylation. Despite those fundamental...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 307–316.
Published: 15 January 2009
...Hongge Jia; Yajuan Liu; Wei Yan; Jianhang Jia The seven-transmembrane protein Smoothened (Smo) and Zn-finger transcription factor Ci/Gli are crucial components in Hedgehog (Hh) signal transduction that mediates a variety of processes in animal development. In Drosophila , multiple kinases have been...
Includes: Supplementary data