... with active genes. However, primed enhancers are marked solely by H3K4me1 prior to the activation of gene transcription ( Creyghton et al., 2010 ). To understand how enhancer-associated chromatin modifications change during the pancreatic endocrine cell fate transition, we mapped H3K4me1 and H3K27ac profiles...

... Fig. S7 ). Although the rapidly changing meiotic chromosomes render precise quantification difficult, meiosis clearly entails further changes in chromatin modifications. * Author for correspondence ( [email protected] ) Competing interests statement The authors declare no competing...

...-independent chromatin de-methylation. This report is one of the first demonstrations of correlation between gene expression, binding of transcription factors and chromatin modification in a developing neural tissue. References Anderson, D. J., Groves, A., Lo, L., Ma, Q., Rao, M., Shah, N. M. and Sommer...