... the mechanisms related to the regulation of the cell cycle and chromatin modifications during the loss of multipotency and lineage specification of progenitor cells. Fig. 7. Model of sequential chromatin regulatory steps during pancreatic endocrine lineage specification. During the transition from Ngn3...

... as stage 1-I, when cell enlargement is also first observed, suggesting an early establishment of an MMC-specific chromatin state. H4K3me3 chromatin modification is catalysed by several enzymes, including Arabidopsis ATX1 and SDG2, as well as other potentially active SET or ATRX proteins ( Alvarez...

...-independent chromatin de-methylation. This report is one of the first demonstrations of correlation between gene expression, binding of transcription factors and chromatin modification in a developing neural tissue. References Anderson, D. J., Groves, A., Lo, L., Ma, Q., Rao, M., Shah, N. M. and Sommer...