...; Maria K. Lehtinen; Vitezslav Bryja ABSTRACT The choroid plexus (ChP) produces cerebrospinal fluid and forms an essential brain barrier. ChP tissues form in each brain ventricle, each one adopting a distinct shape, but remarkably little is known about the mechanisms underlying ChP development. Here, we...

...Filippo Casoni; Laura Croci; Francesca Vincenti; Paola Podini; Michela Riba; Luca Massimino; Ottavio Cremona; G. Giacomo Consalez ABSTRACT The choroid plexus (ChP) is a secretory tissue that produces cerebrospinal fluid (CSF) secreted into the ventricular system. It is a monolayer of secretory...

... a negative influence on choroid plexus differentiation. Thus, our findings identify RA as a novel regulator of chick forebrain RP development. * Author for correspondence ( jonaki@iitk.ac.in ) Competing interests The authors declare no competing or financial interests. 21 1 2015 5 2...

... in driving the continual growth and expansion of the hindbrain choroid plexus throughout development. * Author for correspondence (e-mail: chin.chiang@vanderbilt.edu ) 18 5 2009 © 2009. 2009 Shh Cerebrospinal fluid Choroid plexus Epithelium Gli1 Choroid plexuses (ChPs...

...Itaru Imayoshi; Tomomi Shimogori; Toshiyuki Ohtsuka; Ryoichiro Kageyama The choroid plexus in the brain is unique because it is a non-neural secretory tissue. It secretes the cerebrospinal fluid and functions as a blood-brain barrier, but the precise mechanism of specification of this non-neural...

...). Overexpression of a constitutively active BMPR1A transforms cortical precursors into choroid plexus cells( Panchision et al., 2001 ),suggesting that BMP signaling has the potential to induce the choroid plexus cell fate. Deletion of Bmpr1a , although demonstrating a requirement for BMP signaling in choroid...

...Nina L. Hunter; Susan M. Dymecki Both hindbrain roof plate epithelium (hRPe) and hindbrain choroid plexus epithelium (hCPe) produce morphogens and growth factors essential for proper hindbrain development. Despite their importance, little is known about how these essential structures develop...

... results suggest that loss of cilia leads to altered function of the choroid plexus epithelum, as evidenced by elevated intracellular cAMP levels and increased chloride concentration in the CSF. These data suggest that cilia function is necessary for regulating ion transport and CSF production, as well...

..., IL 60637, USA † Present address: INSERM U106, Hôpital de la Salpêtrière,47 bd de l'Hôpital, 75013 Paris, France 21 7 2003 © 2003. 2003 Cerebellum Cerebellar midline fusion Roof plate Mid/hindbrain morphogenesis Isthmus Velum medullaris Choroid plexus Wnt1...

..., generated from the dorsal neuroepithelium, is severely compromised. The choroid plexus, subcommissural organ and pineal gland either fail to form or are atrophic. These defects are preceded by an increase in cell death at the dorsal midline. Comparison with the phenotype of Wnt1 sw/sw ( swaying ) mutants...

..., Wnt2b , are expressed only at the medial edge of the telencephalon, defining the hem of the cerebral cortex. The Wnt -rich cortical hem is a transient, neuron-containing, neuroepithelial structure that forms a boundary between the hippocampus and the telencephalic choroid plexus epithelium (CPe...

... plexus regions and regions that would normally form nervous tissue in vivo. All tissues were plated onto a basement membrane substratum for culture in vitro. It was found that explants of neural ectoderm that would normally form choroid plexus in vivo, readily differentiated to form choroid plexus-like...

... including cells of the dorsal midline of the neural tube. This expression pattern persisted throughout the embryonic time span studied. At E11.5, expression of Hox-7 became obvious in the neuroepithelium of the forming tela choroida and the telencephelii in areas destined to form the choroid plexus before...