... and fertile single and double homozygous larp6a and larp6b zygotic mutants revealed no defects in muscle structure, and were indistinguishable from heterozygous or wild-type siblings. However, larp6a mutant females produced eggs with chorions that failed to elevate fully and were fragile. Eggs from larp6b...

... groups. Amnion Amnion fate map BMP-SMAD Chorion Clonal analysis Extra-embryonic ectoderm Extra-embryonic–embryonic interface Animals classified as amniotes, including reptiles, birds and mammals, develop extra-embryonic tissues and organs that perform respiration-related, nutritional...

...Marcus O. Muench; Mirhan Kapidzic; Matthew Gormley; Alan G. Gutierrez; Kathryn L. Ponder; Marina E. Fomin; Ashley I. Beyer; Haley Stolp; Zhongxia Qi; Susan J. Fisher; Alicia Bárcena We examined the contribution of the fetal membranes, amnion and chorion, to human embryonic and fetal hematopoiesis...

... to shallow uterine invasion and deficient spiral artery remodeling. We studied the effects of severe PE (sPE) on the smooth chorion portion of the fetal membranes. The results showed a significant expansion of the CTB layer. The cells displayed enhanced expression of stage-specific antigens that extravillous...

... (SynT-II). These genes were also expressed in distinct layers in the chorion as early as E8.5,prior to villous formation. Specifically, Hand1 was expressed in apical cells lining maternal blood spaces ( Ctsq is not expressed until E12.5), Syna in a layer immediately below, and Gcm1,Cebpa and Synb...

...Brandon M. Zeigler; Daisuke Sugiyama; Michael Chen; Yalin Guo; Karen M. Downs; Nancy A. Speck The chorio-allantoic placenta forms through the fusion of the allantois(progenitor tissue of the umbilical cord), with the chorionic plate. The murine placenta contains high levels of hematopoietic stem...