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Keywords: Chondrocyte proliferation
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Journal Articles
Journal: Development
Development (2001) 128 (24): 5099–5108.
Published: 15 December 2001
.... In contrast to Ihh mutants ( Ihh n /Ihh n ), chondrocyte differentiation proceeds normally. However, like Ihh n /Ihh n mice, proliferation of chondrocytes is reduced by about 50%, supporting a direct role for Ihh in the regulation of chondrocyte proliferation. Moreover, by overexpressing either Ihh...
Journal Articles
Journal: Development
Development (2001) 128 (18): 3543–3557.
Published: 15 September 2001
... of limbs and ribs, chondrocyte proliferation was markedly diminished and there was a notable increase of hypertrophic chondrocytes, accompanied by premature ossification of bone. The pattern of expression of genes known to regulate chondrocyte differentiation was not perturbed in Pbx1-deficient cartilage...