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Keywords: Chondrocyte maturation
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Journal Articles

Calcium/calmodulin-dependent protein kinase II activity regulates the proliferative potential of growth plate chondrocytes

Free
Yuwei Li, Molly J. Ahrens, Amy Wu, Jennifer Liu, Andrew T. Dudley
Journal: Development
Development (2011) 138 (2): 359–370.
https://doi.org/10.1242/dev.052324
Published: 15 January 2011
... populations. * Author for correspondence ([email protected]) Competing interests statement 15 11 2010 © 2011. CamkII Kinase Growth plate Cartilage Chondrocyte maturation Transit amplification Adult stem cells Chick Mouse During...
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Includes: Supplementary data
Journal Articles

Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb

Free
Kazu Matsumoto, Yingcui Li, Caroline Jakuba, Yoshinori Sugiyama, Tetsuya Sayo, Misako Okuno, Caroline N. Dealy, Bryan P. Toole, Junji Takeda, Yu Yamaguchi, Robert A. Kosher
Journal: Development
Development (2009) 136 (16): 2825–2835.
https://doi.org/10.1242/dev.038505
Published: 15 August 2009
... and in the expression domains of markers of hypertrophic differentiation in the mutant growth plates, indicating that HA is necessary for the normal progression of chondrocyte maturation. In addition, secondary ossification centers do not form in the central regions of Has2 mutant growth plates owing to a failure...
View article titled, Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb
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Journal Articles

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

Open Access
Daniela Später, Theo P. Hill, Roderick J. O'Sullivan, Michaela Gruber, David A. Conner, Christine Hartmann
Journal: Development
Development (2006) 133 (15): 3039–3049.
https://doi.org/10.1242/dev.02471
Published: 1 August 2006
... of chondrocytes. Accurate chondrocyte maturation is crucial for endochondral ossification and for the ultimate size of skeletal elements, as premature or delayed maturation results predominantly in shortened elements. Wnt9a has previously been implicated as being a player in joint induction, based on gain...
View article titled, Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis
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Includes: Supplementary data