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Keywords: Cholinergic interneurons
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Journal Articles

LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons

Apostolia Fragkouli, Nicole Verhey van Wijk, Rita Lopes, Nicoletta Kessaris, Vassilis Pachnis
Journal: Development
Development (2009) 136 (22): 3841–3851.
https://doi.org/10.1242/dev.038083
Published: 15 November 2009
... that in the absence of Lhx7 only a relatively small fraction of β-gal + SIN progenitors are capable of differentiating into cholinergic interneurons. The LIM HD protein Lhx6 is expressed in MGE-derived cortical GABAergic interneurons and is required for their tangential migration and subtype specification...
View articletitled, LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons
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Includes: Supplementary data