.... Sonic hedgehog Axon guidance Commissural neurons In ovo RNAi Primary cilium Midline crossing Ift88 Arl13b Mouse Chicken Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung http://dx.doi.org/10.13039/501100001711 Deutsche Forschungsgemeinschaft...

...-137 Chicken Agencia Nacional de Promoción Científica y Tecnológica http://dx.doi.org/10.13039/501100003074 PICT 2018-1879 In all chordates, the ectoderm layer becomes segregated into the neural plate (NP) and the surrounding non-neural ectoderm. The NP subsequently folds...

... at tyrosine 489 by Abelson kinase, to the distal axon, which in turn is necessary for the correct navigation of post-crossing commissural axons in the developing chicken spinal cord. * Author for correspondence ( [email protected] ) Handling Editor: James Briscoe Competing interests...

...Martin A. Estermann; Andrew T. Major; Craig A. Smith ABSTRACT During gonadal sex determination, the supporting cell lineage differentiates into Sertoli cells in males and pre-granulosa cells in females. Recently, single cell RNA-seq data have indicated that chicken steroidogenic cells are derived...

... are poorly understood. In this study, we use single-cell transcriptomics to define the cell-fate decisions directing LPM specification, subdivision and early initiation of the forelimb mesenchyme in chicken embryos. We establish a transcriptional atlas and global cell-cell signalling interactions...

... by The Company of Biologists Ltd 2022 Summary: This Review presents the intrinsic and extrinsic mechanical forces acting on the embryonic gut and their determining role in structuring the development of this organ. Biomechanics Intestine Embryo Mouse Chicken Human Université de Paris...

... their long-distance migration and interaction with the anterior mesendoderm to form brain tissues. Epiblast Node Anterior mesendoderm Brain primordia Live imaging Chicken Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691 JP16H06280 JP21K06204...

... physiological (molting) and plucking injury-induced regeneration in chickens. Proliferation analyses reveal quiescent, transient-amplifying (TA) and long-term label-retaining dermal cell (LRDC) states. During the growth phase, LRDCs are activated to make new dermal components with distinct cellular flows...

.... , Ferguson , M. W. J. and Fallon , J. F. ( 2006 ). The development of archosaurian first-generation teeth in a chicken mutant . Curr. Biol. 16 , 371 - 377 . 10.1016/j.cub.2005.12.047 Haycraft , C. J. , Banizs , B. , Aydin-Son , Y. , Zhang , Q. , Michaud , E. J...

... to systematically annotate the functions of lncRNAs in the chicken genome. Co-expression analysis provides a feasible strategy to predict the functions of lncRNAs ( Perron et al., 2017 ; Xu et al., 2017 ; Han et al., 2017 ; Jiang et al., 2015 ; Guo et al., 2013 ; Liao et al., 2011 ). Here, we have...

... kinase (LTK), an ALK-type receptor tyrosine kinase, is expressed by neural crest cells during early migratory stages in chicken embryos. Loss of LTK in the cranial neural crest impairs migration and results in increased levels of apoptosis. Conversely, midkine, previously proposed as a ligand for ALK...

... unclear how the keratinocytes sense this gradient and orient barb growth. Here, we show that in chicken, owing to feather branching, the global Wnt gradient is subdivided into periodic barbs. Within each barb, the anterior barbule plate cells tilt before the posterior cells. The core planar cell polarity...

... of ENS development in mouse and chick, with Col18 expression at the wavefront being permissive and agrin expression post-colonization being inhibitory to ENCDC migration. Enteric nervous system Extracellular matrix Neural crest cells Collagen 18 Agrin Hirschsprung disease Chicken Mouse...

... an optimised, adaptable toolkit enabling genome and epigenome engineering in the chicken embryo, and demonstrate its utility by probing gene regulatory interactions mediated by neural crest enhancers. First, we optimise novel efficient guide-RNA mini expression vectors utilising chick U6 promoters, provide...

..., which is upregulated in mutant lateral LMC motor neurons. Genetic and molecular analyses showed that the mutation acts in the EphA4–Limk1–Cfl1/cofilin–actin pathway to modulate growth cone extension/collapse. In the chicken, both experimental upregulation of Limk1 by electroporation and pharmacological...

... The authors declare no competing or financial interests. 27 6 2017 6 12 2017 © 2018. Published by The Company of Biologists Ltd 2018 Summary: Chicken NFIA prevents hypertrophic differentiation in the interzone/articular region, whereas GATA3 activates articular cartilage-specific...

...Laurent Yvernogeau; Catherine Robin Hematopoietic stem cells (HSCs), which are responsible for blood cell production, are generated during embryonic development. Human and chicken embryos share features that position the chicken as a reliable and accessible alternative model to study developmental...

...Lorna Taylor; Daniel F. Carlson; Sunil Nandi; Adrian Sherman; Scott C. Fahrenkrug; Michael J. McGrew In this work we use TALE nucleases (TALENs) to target a reporter construct to the DDX4 ( vasa ) locus in chicken primordial germ cells (PGCs). Vasa is a key germ cell determinant in many animal...

.... M. , Harland , R. and Wu , D. K. ( 1999 ). Ectopic noggin blocks sensory and nonsensory organ morphogenesis in the chicken inner ear . Dev. Biol.   216 , 369 - 381 . 10.1006/dbio.1999.9457 Chang , W. , ten Dijke , P. and Wu , D. K. ( 2002 ). BMP pathways...

... expression of guidance receptors at choice points. Commissural axon guidance Frizzled 3 RabGDI GDI1 Robo1 Wnt signaling Midline crossing Chicken Attractive and repulsive guidance cues cooperate in the navigation of growing axons to their correct targets during development. On their way...