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Keywords: Chick
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Journal Articles
In collection:
Human development
Journal: Development
Development (2024) 151 (3): dev202098.
Published: 12 February 2024
... induction of NMPs from human embryonic stem cells (hESCs) relies on Notch signalling. Using hESC-derived NMPs and chick embryo grafting, we demonstrate that Notch directs a pro-mesodermal character at the expense of neural fate. We show that Notch also contributes to activation of HOX gene expression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (22): dev202010.
Published: 16 November 2023
... morphogen gradients and tissue mechanics in regulating the collective cell movements that drive hindgut morphogenesis in the chick embryo. Morphogenesis Chemo-mechanical model Hindgut Chick Endoderm National Institute of General Medical Sciences http://dx.doi.org/10.13039/100000057...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2023) 150 (16): dev201651.
Published: 24 August 2023
... from the adherens junctions to the nucleus to stimulate Tcf-dependent transcription in a Wnt-independent manner. This new β-catenin activity regulates genes implicated in several aspects of contralateral axon growth, including axon guidance and adhesion. Using live imaging of ex-vivo chick neural tube...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2023) 150 (11): dev201275.
Published: 5 June 2023
... interests. 5 9 2022 3 5 2023 © 2023. Published by The Company of Biologists Ltd 2023 Highlighted Article: The characterization of vacuoles in chick and quail hemogenic endothelial cells, and the analysis of aquaporin localization suggest that endothelial cell rounding...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (11): dev199660.
Published: 10 June 2022
... understood. Here, we develop a time-lapse imaging strategy to measure the four cell cycle phases in single chick neural progenitor cells in their endogenous environment. We show that neural progenitors are widely heterogeneous with respect to cell cycle length. This variability in duration is distributed...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2021) 148 (9): dev198549.
Published: 30 April 2021
... of daughter cells, such as a cone photoreceptor and a horizontal cell (HC). We used genome-wide assays of chromatin structure to compare the profiles of a restricted cone/HC RPC and those of other RPCs in chicks. These data nominated regions of regulatory activity, which were tested in tissue, leading...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (9): dev188821.
Published: 6 May 2020
...Lara Busby; Cristina Aceituno; Caitlin McQueen; Constance A. Rich; Maria A. Ros; Matthew Towers ABSTRACT Classical tissue recombination experiments performed in the chick embryo provide evidence that signals operating during early limb development specify the position and identity of feathers. Here...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (24): dev181107.
Published: 16 December 2019
... is still debated. Here, we identify a crucial role for the transcription factor PRDM1 in the orderly transition from epiblast to defined neural lineages in chick. PRDM1 is initially expressed broadly in the entire epiblast, but becomes gradually restricted as cell fates are specified. We find that PRDM1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (22): dev171405.
Published: 21 November 2019
... studies suggested that pineal progenitors originate from the lateral border of the anterior neural plate. We show here, using gene expression and fate mapping/lineage tracing in zebrafish, that pineal progenitors originate, at least in part, from the non-neural ectoderm. Gene expression in chick indicates...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (20): dev174318.
Published: 11 October 2019
... Mechanobiology Chick Cerebral hemispheres account for the majority of brain volume in adult humans, and abnormalities during early development can result in dramatic downstream effects. Incomplete hemisphere division, or holoprosencephaly, represents the most common, and often lethal, brain malformation...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2019) 146 (20): dev175729.
Published: 2 October 2019
... miR-19b as crucial for restricting the expression of Wnt7b to the hem region in chick, where it defines the position of the hem and the hippocampus, revealing its importance in regulating avian forebrain patterning. miR-19b Wnt7b Chick Forebrain Hippocampus Hem The avian...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (17): dev176784.
Published: 12 September 2019
..., and the purinergic G-protein-coupled receptor GPR17 plays an essential role in this regulation. GPR17 is highly expressed in the ventral progenitor regions of the neural tube and acts as a negative regulator of the Shh signal in chick embryos. Although the activation of the GPR17-related signal inhibits ventral...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (17): dev165340.
Published: 3 September 2018
... that produces V2 interneurons. Knockdown of RNF220 and ZC4H2 in the chick spinal cord downregulates expression of the V2 interneuronal marker Chx10. Co-expression of RNF220 and ZC4H2 further promotes the ability of Nkx6.1 to induce ectopic Chx10 + V2 interneurons. Our results uncover a novel regulatory pathway...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2018) 145 (8): dev159764.
Published: 16 April 2018
... in the developing mouse and chick pallium, whereas stage-specific binary functions of Pax6 in neurogenesis are unique to mouse neuronal progenitors, consistent with Pax6-dependent temporal regulation of Notch signaling. Furthermore, we identified that Pax6-dependent enhancer activity of Dbx1 is extensively...
Includes: Supplementary data
Journal Articles
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (19): 3521–3532.
Published: 1 October 2017
.... To test this possibility, we combined embryological and molecular approaches in chick embryos to show that, at gastrula stage, adenohypophyseal precursors are clustered in the median preplacodal ectoderm, largely segregated from those of the adjacent olfactory placode. Median precursors are elongated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (18): 3278–3288.
Published: 15 September 2017
... in the embryonic chick. Presumptive hypothalamic cells derive from the rostral diencephalic ventral midline, lie above the prechordal mesendoderm and express Fgf10 . Fgf10 + progenitors undergo anisotropic growth: those displaced rostrally differentiate into anterior cells, then those displaced caudally...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (8): 1531–1543.
Published: 15 April 2017
... and transcriptional inputs that act sequentially and/or in parallel. Using the chick embryo, we uncover novel genes in the gene regulatory network underlying otic commitment and reveal dynamic changes in gene expression. Functional analysis of selected transcription factors reveals the genetic hierarchy underlying...
Includes: Supplementary data