... that the original work is properly attributed. Summary: Deletion of the fms -intronic regulatory element of Csf1r in mouse disrupts the engraftment and maintenance of central nervous system macrophages in a compartment-specific manner. Phagocytes Myeloid cells Kolmer cells Cerebrospinal fluid...

... embryo and discuss the role of flow of blood, lymph and cerebrospinal fluid in sculpting the embryonic cardiovascular and nervous system. * These authors contributed equally to this work ‡ Author for correspondence ( [email protected] ) Competing interests The authors declare...

...Zakia Abdelhamed; Shawn M. Vuong; Lauren Hill; Crystal Shula; Andrew Timms; David Beier; Kenneth Campbell; Francesco T. Mangano; Rolf W. Stottmann; June Goto ABSTRACT Pediatric hydrocephalus is characterized by an abnormal accumulation of cerebrospinal fluid (CSF) and is one of the most common...

...Pia A. Johansson; Martin Irmler; Dario Acampora; Johannes Beckers; Antonio Simeone; Magdalena Götz The choroid plexuses (ChPs) are the main regulators of cerebrospinal fluid (CSF) composition and thereby also control the composition of a principal source of signaling molecules that is in direct...

...Xi Huang; Tatiana Ketova; Jonathan T. Fleming; Haibin Wang; Sudhansu K. Dey; Ying Litingtung; Chin Chiang Choroid plexuses (ChPs) are vascularized secretory organs involved in the regulation of brain homeostasis, and function as the blood-cerebrospinal fluid(CSF) barrier. Despite their crucial...