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Keywords: Central nervous system
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Journal Articles
Journal: Development
Development (2024) 151 (3): dev201829.
Published: 5 February 2024
...Linh Thi My Nguyen; Shaoli Hassan; Hongru Pan; Shuting Wu; Zilong Wen ABSTRACT In vertebrates, the central nervous system (CNS) harbours various immune cells, including parenchymal microglia, perivascular macrophages and dendritic cells, which act in coordination to establish an immune network...
Includes: Supplementary data
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Neural development
Journal: Development
Development (2022) 149 (13): dev200597.
Published: 7 July 2022
... an essential role for Pinch2 during central nervous system myelination. Unlike Pinch1 gene ablation, loss of Pinch2 in oligodendrocytes results in hypermyelination and in the formation of pathological myelin outfoldings in white matter regions. These structural changes concur with inhibition of Rho GTPase RhoA...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (14): dev181495.
Published: 15 July 2020
.... Central nervous system Fate decisions Stochasticity In the biological literature, developmental processes are frequently classified as deterministic or stochastic. This classification is often based on the reproducibility of an outcome of a biological experiment. For example, if an experiment...
Journal Articles
Journal: Development
Development (2020) 147 (14): dev181495.
Published: 15 July 2020
.... In light of these considerations, we then review and interpret several recent findings relating to cell fate decisions during central nervous system (CNS) development. In the biological literature, developmental processes are frequently classified as deterministic or stochastic. This classification...
Journal Articles
Journal: Development
Development (2017) 144 (19): 3417–3429.
Published: 1 October 2017
...Brett J. Hilton; Frank Bradke In the adult mammalian central nervous system (CNS), neurons typically fail to regenerate their axons after injury. During development, by contrast, neurons extend axons effectively. A variety of intracellular mechanisms mediate this difference, including changes...
Journal Articles
Journal: Development
Development (2017) 144 (15): 2714–2718.
Published: 1 August 2017
... determination during development and directed reprogramming. Brain Cellular plasticity Cellular reprogramming Developmental programme Central nervous system For two days in April 2017, organizers Paola Arlotta (Harvard University, USA), Benedikt Berninger (Mainz University, Germany) and Marisa...
Journal Articles
Journal: Development
Development (2017) 144 (15): 2714–2718.
Published: 1 August 2017
... determination during development and directed reprogramming. Brain Cellular plasticity Cellular reprogramming Developmental programme Central nervous system European Research Council SFB870 SPP1738 SPP1757 648960 Fondation ARC pour la Recherche sur le Cancer SFI20121205880...
Journal Articles
Journal: Development
Development (2016) 143 (8): 1290–1301.
Published: 15 April 2016
...: Characterisation of the neural stem cells in the gnathal head region completes the mapping of all individual neuroblasts that generate the Drosophila CNS. Central nervous system Neuroblasts Segmental patterning Drosophila brain Gene expression profile Deformed The development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (22): 4366–4374.
Published: 15 November 2014
...Marta Moris-Sanz; Alicia Estacio-Gómez; Javier Álvarez-Rivero; Fernando J. Díaz-Benjumea During the development of the central nervous system, neural progenitors generate an enormous number of distinct types of neuron and glial cells by asymmetric division. Intrinsic genetic programs define...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (10): 2046–2056.
Published: 15 May 2014
.... Central nervous system Drosophila ELAV/Hu Hox RNA-binding protein RNA processing Alternative polyadenylation (APA) Alternative splicing Segment-specific apoptosis The nervous system of vertebrates and invertebrates shows a remarkable level of regionalisation along the anteroposterior (AP...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: Primer Series
Development (2012) 139 (15): 2643–2653.
Published: 1 August 2012
... research is shaping our understanding of their evolution. This includes evolution of developmental genes and networks and our changing views of their conservation and divergence across the animals; the evolution of segmentation and the central nervous system and the debates about what is conserved...
Journal Articles
Journal: Development
Development (2008) 135 (23): 3839–3848.
Published: 1 December 2008
... Syndrome. * Author for correspondence (e-mail: tkidd@unr.edu ) 22 9 2008 © 2008. 2008 Drosophila genetics Axon guidance Body patterning Cell migration Central nervous system Signal transduction In bilaterally symmetric nervous systems, many axons are guided...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2007) 134 (11): 2147–2158.
Published: 1 June 2007
... ; Joly et al., 1992 ; Marom et al., 1997 ; Meyer and Gruss, 1993 ; Nordstrom et al., 2006 ; Pillemer et al., 1998 ; Reece-Hoyes et al., 2002 ). One of the most prominent characteristics that distinguishes the rostral and caudal regions of the vertebrate central nervous system (CNS) is its...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (14): 3423–3432.
Published: 15 July 2004
... Stem cell Central nervous system Neurosphere As development proceeds and the CNS becomes a complex three-dimensional structure, the neural stem cells that generate all three major cell lineages in the CNS, neurones, astrocytes and oligodendrocytes, become restricted to specialised germinal...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2002) 129 (6): 1423–1434.
Published: 15 March 2002
... suggests an independent Pax6 duplication in a triclad or platyhelminth ancestor. Pax6A is expressed in the central nervous system of intact planarians, labeling a subset of cells of both cephalic ganglia and nerve cords, and is activated during cephalic regeneration. Pax6B follows a similar pattern...
Journal Articles
Journal Articles