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Keywords: Celsr1
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Journal Articles

Celsr1 suppresses Wnt5a -mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons

In collection:
Neural development
Devynn Hummel, Alexandria Becks, Hongsheng Men, Elizabeth C. Bryda, Derrick M. Glasco, Anand Chandrasekhar
Journal: Development
Development (2022) 149 (22): dev200553.
https://doi.org/10.1242/dev.200553
Published: 16 November 2022
... the mechanisms regulating initiation of FBM neuron migration are well defined, those regulating directionality are not. In mutants lacking the Wnt/planar cell polarity (PCP) component Celsr1, many FBM neurons inappropriately migrate rostrally into r3. We hypothesized that Celsr1 normally blocks inappropriate...
View article titled, <span class="search-highlight">Celsr1</span> suppresses Wnt5a -mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons
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Includes: Supplementary data
Journal Articles

New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo

Lena P. Basta, Michael Hill-Oliva, Sarah V. Paramore, Rishabh Sharan, Audrey Goh, Abhishek Biswas, Marvin Cortez, Katherine A. Little, Eszter Posfai, Danelle Devenport
Journal: Development
Development (2021) 148 (18): dev199695.
https://doi.org/10.1242/dev.199695
Published: 23 September 2021
... and dynamics of transmembrane PCP proteins: Celsr1, Fz6 and Vangl2. Using the skin epidermis as a model, we characterize and verify the expression, localization and function of endogenously tagged Celsr1-3xGFP, Fz6-3xGFP and tdTomato-Vangl2 fusion proteins. Live imaging of Fz6-3xGFP in basal epidermal...
View article titled, New mouse models for high resolution and live imaging of planar cell polarity proteins in vivo
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Includes: Supplementary data