... 2013. Published by The Company of Biologists Ltd Retina development DNA methylation Cell-cell interaction Morphogenesis Epigenetics Mouse In retinal and macular neurodegenerative diseases, such as retinitis pigmentosa (RP) and age-related macular degeneration (AMD), vision...

...Athena R. Ypsilanti; Yvrick Zagar; Alain Chédotal In most tissues, the precise control of cell migration and cell-cell interaction is of paramount importance to the development of a functional structure. Several families of secreted molecules have been implicated in regulating these aspects...

... ), these results strongly suggest that different levels of endogenous Dll1 regulate the neuronal differentiation of NPCs via cell-cell interaction, most likely through the lateral inhibitory system. Fig. 6. Dll1 deletion in a large number of NPCs in the developing mouse telencephalon induces...

... genus Helobdella . In leech, the O and P lineages arise from a developmental equivalence group of O/P teloblasts. In this study, we demonstrate that the cell-cell interactions involved in cell fate specification of the O/P equivalence group differ among three laboratory colonies of closely related...

... for correspondence (e-mail: [email protected] ) 9 1 2003 © 2003. 2003 Drosophila Germ cells Cell-cell interaction E-cadherin Morphogenesis Gonad coalescence Tracheal development LIV1 Germ cells follow a complex developmental program in order to form the gametes and give rise...

...Kenji Matsuno; Mikiko Ito; Kazuya Hori; Fumiyasu Miyashita; Satoshi Suzuki; Noriyuki Kishi; Spyros Artavanis-Tsakonas; Hideyuki Okano The Notch pathway is an evolutionarily conserved signaling mechanism that is essential for cell-cell interactions. The Drosophila deltex gene regulates Notch...

...Caroline Goutte; William Hepler; Katherine M. Mickey; James R. Priess ABSTRACT In animal development, numerous cell-cell interactions are mediated by the GLP-1/LIN-12/NOTCH family of transmembrane receptors. These proteins function in a signaling pathway that appears to be conserved from nematodes...

... that these non-autonomous effects are likely caused by cell-cell interactions between keratinocytes within the hair follicle and that Notch may function in such interactions either by directing the differentiation of follicular cells or assisting cells in interpreting a gradient emanating from the dermal papilla...

... interaction during eye development. 25 06 1997 © 1997 by Company of Biologists 1997 sidekick immunoglobulin superfamily cell-cell interaction Drosophila eye development photoreceptor cell The Drosophila eye comprises eight photoreceptor (R) cells, four cone cells, three...

[email protected] 28 02 1995 © 1995 by Company of Biologists 1995 Suppressor of Hairless Notch lateral inhibition neurogenesis peripheral nervous system cell-cell interaction Intercellular signals play major roles in specifying cell fates during animal development...

... that N-cadherin is functionally required in mediating the cell-cell interactions among mesenchymal cells important for chondrogenesis in micromass culture in vitro and in the intact limb bud in vivo. * Author for correspondence 14 10 1993 © 1994 by Company of Biologists 1994 cell...

... and thus an essential role in the morphogenesis of the organism. The use of extracellular matrix receptors in this role may aid in keeping the different cell layers distinct. © The Company of Biologists Limited 1993 1993 integrins morphogenesis Drosophila extracellular matrix cell-cell...

... and deltex may participate in a common scheme of cell-cell interactions ( Artavanis-Tsakonas and Simpson, 1991 ). Two members of this group, Ser and dx , are not neurogenic genes ( Fleming et al., 1990 ; Thomas et al., 1991 ; Xu and Artavanis-Tsakonas, 1990 ), yet they interact prominently with Notch...

... by analysis of mutant phenotypes in the embryonic somatic muscles and the eye imaginal disk. The expression patterns and mutant phenotypes indi- cate a role for abl in establishing and maintaining cell- cell interactions. To examine phenotypes in abl mutant eye imaginal disks, abl mutant ( abl 4 / Df...

... mechanistic framework. Differential spatial expression of histospecific genes is considered in terms of the structure of the gene regulatory network that will be required in embryos that utilize cell–cell interaction, autonomous vs conditional specification and maternal spatial information to differing...

...Judith Austin; Eleanor M. Maine; Judith Kimble ABSTRACT Cell-cell interactions play a significant role in controlling cell fate during development of the nematode Caenorhabditis elegans . It has been found that two genes, glp-1 and lin-12 , are required for many of these decisions, glp-1...