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Keywords: Cell survival
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Journal Articles
Journal: Development
Development (2018) 145 (20): dev164046.
Published: 24 October 2018
... binds to LTK. Taken together, these results suggest that LTK in neural crest cells interacts with midkine emanating from the non-neural ectoderm to promote cell survival, revealing a new signaling pathway that is essential for neural crest development. * Author for correspondence ( mbronner...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (9): dev156018.
Published: 25 April 2018
... innate immunity in determining cell fate and differentiation, including during competition for light in plants and in neurotrophism and plasticity in the CNS. Toll Tol-1 TLR TIR-NBS-LRR Sarm MyD88 NF-κB Dorsal Wek JNK FoxO Cell death Cell survival Cell fate Cell proliferation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2907–2919.
Published: 15 August 2016
... ). Cellular stress responses: cell survival and cell death . Int. J. Cell Biol.   2010 , 214074 . 10.1155/2010/214074 Garelli , A. , Gontijo , A. M. , Miguela , V. , Caparros , E. and Dominguez , M. ( 2012 ). Imaginal discs secrete insulin-like peptide 8 to mediate plasticity...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (24): 5379–5391.
Published: 15 December 2011
... ; Bertrand and Traver, 2009 ). Correlation of hemocyte residency with elevated proliferation levels and anti-apoptotic cell survival are consistent with the idea that inductive and trophic local microenvironments support hemocytes in epidermal-muscular pockets. Using gain- and loss-of-function analyses...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (13): 2321–2329.
Published: 1 July 2008
...-catenin/Wnt signaling in dermal development. * Author for correspondence (e-mail: rpa5@case.edu ) 10 5 2008 © 2008. 2008 Dermis Cell fate Cell survival Skin Sternum To identify whether Wnt/β-catenin signaling is active during ventral dermal specification...
Journal Articles
Journal: Development
Development (2007) 134 (7): 1443–1451.
Published: 1 April 2007
... upregulation, in addition to being necessary for the nuclear translocation of Mdm2. Inhibition of either mTOR or Mdm2 is sufficient to block cell survival induced by Hgf-Met in vitro. Moreover, in vivo inhibition of mTOR downregulates Mdm2 protein levels and induces p53-dependent apoptosis. Our studies...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (23): 4771–4781.
Published: 1 December 2006
... concerning the genes required for survival during the early cell-proliferation phase. Here, we show that Lobe ( L ) and the Notch (N) ligand Serrate ( Ser ), which are both involved in ventral eye growth, are required for cell survival in the early eye disc. We observed that the loss-of-ventral-eye phenotype...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (12): 2435–2445.
Published: 15 June 2006
.... 2006 Fgf8 Anterior heart field Cardiogenesis Cell Survival Proliferation Pea3 Bmp4 Erk Mouse Myocardial progenitors are derived from early migratory mesoderm that forms bilateral heart fields. These populations organize and coalesce generating the heart field...
Journal Articles
Journal: Development
Development (2006) 133 (10): 1871–1880.
Published: 15 May 2006
... for correspondence (e-mail: abergman@mdanderson.org ) 10 3 2006 © 2006. 2006 Vps25 ESCRT Protein sorting MVB Notch Cell proliferation Cell survival Apoptosis The regulation of tissue homeostasis involves the concerted action of several signaling pathways...
Journal Articles
Journal: Development
Development (2006) 133 (6): 1079–1089.
Published: 15 March 2006
... a transient phase of cell death, which affects most, but not all adenohypophyseal cells. Surviving cells form a smaller pituitary rudiment,lack expression of specific adenohypophyseal marker genes ( pit1,neurod ), while expressing others ( lim3, pitx3 ), and display an ultrastructure reminiscent of precursor...
Journal Articles
Journal: Development
Development (2006) 133 (3): 517–528.
Published: 1 February 2006
... Cell proliferation Cell survival Hedgehog signaling Gli proteins Chick The early embryonic vertebrate neural tube is composed of proliferating progenitors and terminally differentiating neurons distributed in a characteristic arrangement. Mitotically active cells form a pseudostratified...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (18): 4545–4553.
Published: 15 September 2004
... cells and pole cell-specific expression of wun2 rescued the pole cell death phenotype of the maternal wun2 mutant, suggesting that wun2 activity in pole cells is required for their survival. Furthermore, we obtained genetic evidence that pole cell survival requires a proper balance of LPP activity...
Journal Articles
Journal: Development
Development (2004) 131 (15): 3681–3692.
Published: 1 August 2004
... of Sheffield, Department of Biomedical Science,Firth Court, Western Bank, Sheffield S10 2TN, UK 21 4 2004 © 2004. 2004 Fgf3 Pituitary Adenohypophysis Neurohypophysis Zebrafish Lia Cell survival Cell specification Apoptosis Sonic Hedgehog The pituitary gland links...
Journal Articles
Journal: Development
Development (2003) 130 (20): 4919–4929.
Published: 15 October 2003
... 4 7 2003 © 2003. 2003 Antisense morpholino oligo Cell survival Emx2 ERK Gastrulation Neurulation Xenopus The vertebrate forebrain consists of anatomically and functionally distinct domains patterned along their anteroposterior and dorsoventral axis (reviewed...
Journal Articles
Journal: Development
Development (2001) 128 (20): 4011–4020.
Published: 15 October 2001
... counteract a built-in cell death program and thereby contribute to organ morphogenesis, in particular in the central nervous system. *Author for correspondence (e-mail: teillet@infobiogen.fr ) 19 7 2001 © 2001. 2001 Apoptosis Avian embryo Cell death Cell survival Floor plate...
Journal Articles
Journal: Development
Development (2001) 128 (19): 3819–3830.
Published: 1 October 2001
... conclude that the majority of the cell number differences between wild-type and Igf2 +m/−p mice can be accounted for by modification of cell survival and proliferation during the period (E9 to E10) of post-implantation development. *Author for correspondence (e-mail: bass.hassan@zoo.ox.ac.uk ) 5...