... Tissue morphogenesis Cell shape FGF Rho Rac Mouse Japan Society for the Promotion of Science http://dx.doi.org/10.13039/501100001691 JP21K06206 National Institutes of Health R01 EY03177 the Ophthalmic Research Institute of Australia http://dx.doi.org/10.13039...

... platforms and EB1-dependent microtubule growth, tunes cell and tissue contractility by modulating actomyosin dynamics through the spatiotemporal regulation of RhoGTPase activity. Dorsal closure Amnioserosa Cell shape Non-centrosomal microtubule organizing centers Microtubule growth RhoGTPase...

...Sara Caviglia; Iris A. Unterweger; Akvilė Gasiūnaitė; Alexandre E. Vanoosthuyse; Francesco Cutrale; Le A. Trinh; Scott E. Fraser; Stephan C. F. Neuhauss; Elke A. Ober ABSTRACT Visualizing cell shapes and interactions of differentiating cells is instrumental for understanding organ development...

... to the quality of image segmentation: a single strongly erroneous angle measurement can affect inferred tension values over the entire tissue ( Brodland et al., 2014 ). When detailed information of individual cell shape is not required or when poor image quality or large cell number render segmentation...

... are too often simplified as prismatic blocks with a limited plasticity. However, there is increasing evidence that a realistic approach, even from a reductionist perspective, must include apico-basal intercalations (i.e. scutoidal cell shapes) for explaining epithelial organization convincingly. Here, we...

..., including sustained upregulation of Bmp4 expression and the inability of mutant epicardial cells to transition into a mature squamous phenotype. We identified Bmp4 as a transcriptional target of Wt1, thus providing a molecular basis for the retention of the cuboidal cell shape observed in the Wt1KO...

... to identify mechanisms that mediate basal tissue folding to form the highly conserved embryonic midbrain-hindbrain boundary. Live imaging revealed Wnt5b as a mediator of anisotropic epithelial cell shape, both apically and basally. In addition, we uncovered a Wnt5b-mediated mechanism for specific regulation...

... by applying it to the complex shaped pavement cells of Arabidopsis thaliana wild-type and speechless leaves, and Drosophila amnioserosa cells. To validate our method's applicability to large populations, we analysed computer-generated tissues. By controlling in silico cell shape, we explored the potential...

... the canonical Hippo pathway in different epithelial tissues. Cell shape Drosophila Hippo pathway Mechanosensing Yorkie Cancer Research UK 10.13039/501100000289 FC001180 Medical Research Council FC001180 Wellcome Trust 10.13039/100010269 102853/B/13/Z...

...François Graner; Daniel Riveline In two chapters of his book On Growth and Form , D'Arcy Thompson used numerous biological and physical observations to show how principles from mathematics and physics – such as pressure differences, surface tension and viscosity – could explain cell shapes...

... identifies a primary role for α-Spectrin in controlling cell shape, perhaps by modulating actomyosin. In summary, we suggest that a functional spectrin-integrin complex is essential to balance adequate forces, in order to maintain a monolayered epithelium. References Abdelilah-Seyfried , S. , Cox...

... of Celsr1 -deficient mice ( Ravni et al., 2009 ), we found Celsr1 was required for the orchestration of the direction of ciliary movements, the proper epithelial cell shapes and arrangements, and the orderly patterned alignment of epithelial folds in the longitudinal direction. We focused...

.... 1 4 2014 4 6 2014 © 2014. Published by The Company of Biologists Ltd 2014 Islet LIM domain Ascidian Cell shape Palps Placode Ascidians belong to the Subphylum Tunicata, and, as such, represent the sister group to the vertebrates ( Delsuc et al., 2006...

...Amir Bitan; Ido Rosenbaum; Uri Abdu Within interphase cells, microtubules (MTs) are organized in a cell-specific manner to support cell shape and function. Here, we report that coordination between stable and dynamic MTs determines and maintains the highly elongated bristle cell shape. By following...

... 2010 © 2010. Auditory outer hair cell Cell shape Cell-cell junctions Mechanosensitivity Hair bundle Electromotility Planar polarity Myosin VIIa Myosin II Shroom2 Actin Cochlear amplifier Mouse Fig. 6. Redistribution of cell-cortex proteins...

...Jennifer H. Gutzman; Hazel Sive We demonstrate that in the zebrafish hindbrain, cell shape, rhombomere morphogenesis and, unexpectedly, brain ventricle lumen expansion depend on the contractile state of the neuroepithelium. The hindbrain neural tube opens in a specific sequence, with initial...

... . Detailed phenotypic analysis of a phmyb1 mutant confirmed the role of PhMYB1 in the control of cell morphogenesis in the petal epidermis. The phmyb1 mutant showed that epidermal cell shape affects petal presentation, a phenotypic trait also observed following re-examination of mixta mutants. This suggests...

... and restricted to small angle adjustments. Disruption of astral microtubules leads to misalignment of the spindle. These results show that a mechanism of spindle orientation that depends on cell shape rather than cortical polarity can nevertheless generate cell fate diversity from a population of polarised cells...

...Mathias Köppen; Beatriz García Fernández; Lara Carvalho; Antonio Jacinto; Carl-Philipp Heisenberg Epithelial morphogenesis depends on coordinated changes in cell shape, a process that is still poorly understood. During zebrafish epiboly and Drosophila dorsal closure, cell-shape changes...

... of Biology, Yonsei University, Sinchon 134,Seoul, Korea 19 1 2005 ©2005. 2005 Trichomes Cell shape Redundancy GLABRA1 (GL1) One important evolutionary mechanism that creates new gene functions is the duplication and functional diversification of genes. In principle...