... and influence Suzanne Eaton's work has had, and still has, on planar cell polarity-associated studies. Drosophila PCP Cell mechanics Cell polarity During developmental patterning and organogenesis, all tissues need to attain specific, characteristic shapes and sizes. While cell proliferation...

... and biochemical details of this remodeling are fairly well understood, little is known about the change in cell mechanical properties during the process. In this study, we investigated changes in the mechanical phenotype of murine fetal neural progenitor cells (fNPCs) during reprogramming to induced pluripotent...

... effects of pro-apoptotic genes and caspase activity (DIAP1 overexpression) on the rates of apical constriction. This suggests that apoptotic regulators must regulate cytoskeletal organisation and cell mechanics. A question that arises is whether both classes of regulators function in the linear hierarchy...