... remains to be examined. To address this issue, we used the fly eye, where the cone cells exchange neighbors over ∼10 h to shape the lens. We uncovered three pathways regulating this slow mode of cell intercalation. First, we found a limited requirement for MyosinII. In this case, mathematical modeling...

..., little is known about the tissue origin of BM components and their dynamics in vivo . Here, we unravel the assembly and role of the BM main component, Collagen type IV (ColIV), in Drosophila ovarian stalk morphogenesis. Stalks are short strings of cells assembled through cell intercalation that link...

..., individual DBs elongate as a cluster of cells, led by tip cells at the front and trailing cells in the rear. Branch elongation is accompanied by extensive cell intercalation and cell lengthening of the trailing stalk cells. Although cell intercalation is governed by Myosin II (MyoII)-dependent forces during...

...Elise Walck-Shannon; David Reiner; Jeff Hardin Cell intercalation is a fundamental, coordinated cell rearrangement process that shapes tissues throughout animal development. Studies of intercalation within epithelia have focused almost exclusively on the localized constriction of specific apical...

... kinase Pak exhibit a novel phenotype, in which two side-by-side cysts are encapsulated at a time, generating paired egg chambers. This striking phenotype originates in the pupal ovary, where the developing germarium is shaped by the basal stalk, a stack of cells formed by cell intercalation. The process...

... and extension. Both collective cell migration and cell intercalation are thought to drive CE and are used to different degrees in various species as they elongate their body axis. Here, we provide an overview of CE as a general strategy for body axis elongation and discuss conserved and divergent mechanisms...

... grafting of the endodermal layer reveals that endodermal signalling is required for DV cell intercalation during APT maturation up to stage HH5, as well as for induction and maintenance of the expression of Six3 at the neural border. We also show that FGF8 can mimic this inductive effect, and suggest...

... that encircle the future invagination site. The cells in the rows align to form a smooth boundary(`boundary smoothing'), accompanied by a transient increase in myosin at the boundary and cell intercalation oriented in parallel with the cellular rows. Cells then undergo apical constriction and invaginate...

... © 1999 by Company of Biologists 1999 Xenopus laevis Gastrulation Involution Mesoderm Endoderm Marginal zone Cell intercalation Morphogenesis Gastrulation is the morphogenetic process by which, in metazoans, the germ layers are established in their characteristic spatial...

...John Shih; Ray Keller ABSTRACT In Xenopus , convergence and extension are produced by active intercalation of the deep mesodermal cells between one another along the mediolateral axis (medi- olateral cell intercalation), to form a narrower, longer array. The cell motility driving this intercalation...

...John Shih; Ray Keller ABSTRACT In a companion paper (Shih, J. and Keller, R. (1992) Development 116, 901-914), we described a sequence of cell behaviors, called mediolateral intercalation behavior (MIB), that produces mediolateral cell intercalation, the process that drives convergence...

... radial intercalation, or exchange of cells between layers. During the second half of gastrulation, the expiants begin to converge strongly toward the midline while continuing to extend vigorously. This second phase of extension is driven by mediolateral cell intercalation, the rearrangement of cells...