... and invertebrates. * Author for correspondence ( psaftig@biochem.uni-kiel.de ) Competing interests statement The authors declare no competing financial interests. © 2012. Published by The Company of Biologists Ltd 2012 ADAM Notch Ectodomain shedding Cell fate determination Differentiation...

... identity. This bi-potency is lost in mature DG cells, although Prox1 is still required for correct gene expression in DG granule cells. Thus, our data indicate that Prox1 acts as a postmitotic cell fate determinant for DG granule cells over the CA3 pyramidal cell fate and is crucial for maintenance...

... for correspondence ( tomreh@u.washington.edu ) Blimp1 (Prdm1) Retina Cell fate determination Photoreceptor Rod Cone Bipolar cell Mouse The retina comprises seven primary cell types: rod and cone photoreceptors, amacrine cells, retinal ganglion cells (RGCs), horizontal cells...

...Lily L. Wong; David H. Rapaport Extrinsic cues and intrinsic competence act in concert for cell fate determination in the developing vertebrate retina. However, what controls competence and how precise is the control are largely unknown. We studied the regulation of competence by examining...

... for specifying neuronal fates that only become definable postnatally. * Author for correspondence (e-mail: SAA2007@med.cornell.edu ) 2 2 2008 © 2008. 2008 Cell fate determination GABA Medial ganglionic eminence Nkx2.1 Parvalbumin Somatostatin Mouse Over the past two...

...Torsten Bossing; Andrea H. Brand The Drosophila ventral midline has proven to be a useful model for understanding the function of central organizers during neurogenesis. The midline is similar to the vertebrate floor plate, in that it plays an essential role in cell fate determination...

... 28 9 2004 © 2004. 2004 Pre-placodal ectoderm Neural crest foxD3 zic2 sox2 sox3 keratin dlx5 dlx6 Cell fate determination Patterning Xenopus It was discovered over a century ago that the cranial sensory organs of vertebrates arise from discrete areas...

... Neuroepithelium Subventricular zone Asymmetric cell division Cell migration Cell cycle Cell fate determination Layer formation Neurogenin2 Slice culture Mouse Asymmetric cell division events are important for the generation of cellular diversity in the mammalian cortex. Recent lineage tracing...

...Fred Tata; David A. Hartley Molecular and genetic data predict that the Enhancer of split locus functions at the end of a pathway dictating appropriate cell fate determination in a number of developmental contexts. We have sought to dissect the role individual member genes of the complex play...