... Tubulin-binding co-factor Cd1 (TBCCd1) protein, indicating that TBCCd1 and PP2A are two essential components of the cellular machinery that regulates the first cell division and mediates basal cell fate determination. The mechanisms underlying the onset of early development from an initial cell...

... and invertebrates. * Author for correspondence ([email protected]) Competing interests statement The authors declare no competing financial interests. © 2012. Published by The Company of Biologists Ltd 2012 ADAM Notch Ectodomain shedding Cell fate determination Differentiation...

... identity. This bi-potency is lost in mature DG cells, although Prox1 is still required for correct gene expression in DG granule cells. Thus, our data indicate that Prox1 acts as a postmitotic cell fate determinant for DG granule cells over the CA3 pyramidal cell fate and is crucial for maintenance...

... , 749 - 756 . Livesey F. J. , Cepko C. L. (2001). Vertebrate neural cell-fate determination: lessons from the retina . Nat. Rev. Neurosci. 2 , 109 - 118 . Livne-Bar I. , Pacal M. , Cheung M. C. , Hankin M. , Trogadis J. , Chen D. , Dorval K. M...

...Lily L. Wong; David H. Rapaport Extrinsic cues and intrinsic competence act in concert for cell fate determination in the developing vertebrate retina. However, what controls competence and how precise is the control are largely unknown. We studied the regulation of competence by examining...

... for specifying neuronal fates that only become definable postnatally. * Author for correspondence (e-mail: [email protected]) 2 2 2008 © 2008. 2008 Cell fate determination GABA Medial ganglionic eminence Nkx2.1 Parvalbumin Somatostatin Mouse Over the past two...

...Torsten Bossing; Andrea H. Brand The Drosophila ventral midline has proven to be a useful model for understanding the function of central organizers during neurogenesis. The midline is similar to the vertebrate floor plate, in that it plays an essential role in cell fate determination...

... tissues (Schlosser and Northcutt, 2000 ; Baker and Bronner-Fraser, 2001). Pre-placodal ectoderm Neural crest foxD3 zic2 sox2 sox3 keratin dlx5 dlx6 Cell fate determination Patterning Xenopus © 2004. 2004 28 9 2004 † Present address: Department...

..., the detection of irreversible cell fate determination at very similar time points with these two completely different approaches is remarkable. Another sign for intracellular events that might be accompanied by or linked with fate determination was detected in earlier timing(Fig. 8B,C , lower panels...

... epithelium to signal properly to the retina. * Author for correspondence (e-mail: [email protected]) 17 10 2000 27 11 2000 © 2001 by Company of Biologists 2001 Cell fate determination Danio rerio Eye Mutation Polarity Proliferation RPE Two major...

...J. Lisa Zheng; Jianyong Shou; Francois Guillemot; Ryoichiro Kageyama; Wei-Qiang Gao ABSTRACT Hair cell fate determination in the inner ear has been shown to be controlled by specific genes. Recent loss-of-function and gain-of-function experiments have demonstrated that Math1 , a mouse homolog...

... neurogenesis. ‡ Author for correspondence (e-mail: [email protected]) * These authors contributed equally to the work 28 03 2000 23 05 2000 © 2000 by Company of Biologists 2000 Alzheimer’s disease Hes5 Dili Notchl Cell fate determination Brain PS1...

... Researcher § Present address: National Institute of Genetics, Mishima, Shizuoka 411-8540, Japan ¶ Author for correspondence (e-mail: [email protected]) 6 April 1999 9 February 1999 © 1999 by Company of Biologists 1999 glial cells missing (gcm) Cell fate...

... Normale Supérieure de Lyon, Reconnaissance Cellulaire et Amélioration des Plantes, 69364 Lyon-cedex 07, France 06 05 1998 10 03 1998 © 1998 by Company of Biologists 1998 Fucus embryogenesis Laser microsurgery Pattern formation Cell fate determination Positional...

... of Biologists 1997 Drosophila sense organ neuronal identity cell fate determination The sensory neurons of arthropods belong to either of two main types, called type I and type II (Zacharuk, 1985). Type I neurons are characterized by their single dendrite whose distal part is a modified...

... 1995 by Company of Biologists 1995 XlPOU 2 neural induction POU noggin Xenopus blastomere cell fate determination The mechanisms for determining what prompts a cell to select an epidermal versus neuronal pathway are not well understood, but the process probably involves...

... that gives rise to the stage 1 egg chamber in germarial region 3. Drosophila oogenesis cell fate determination RNA localization cytoskeleton © 1994 by Company of Biologists 1994 05 02 1994 Fig. 7. Reconstruction of a Bic-D null egg chamber...

...Fred Tata; David A. Hartley ABSTRACT Molecular and genetic data predict that the Enhancer of split locus functions at the end of a pathway dictating appropriate cell fate determination in a number of developmental contexts. We have sought to dissect the role individual member genes of the complex...

... 1991 © 1992 by Company of Biologists 1992 rat retina rod photoreceptor cell cell fate determination reaggregate culture transfilter culture The vertebrate retina contains Müller glial cells, photoreceptors (rods and cones) and a variety of neurons, all of which develop from...

... this question we have studied the temporal and functional requirements for sevenless , a gene controlling the development of a particular cell type in the eye of Drosophila . sevenless eye development cell fate determination conditional allele phototaxis © 1989 by Company of Biologists...