.../ Summary: The embryos expressing Nf2 mutant genes reveal how the orchestration of cell-surface components, including NF2, LATS2 and Ezrin, modulates the Hippo pathway during cell polarization. Nf2 Lats2 Ezrin Hippo pathway Embryo Cell fate decision Japan Society for the Promotion...

... of developmental and synthetic biological circuits. Cell fate decision Dynamical systems Gene regulation Landscape Mathematical modelling Tempo Imperial College London http://dx.doi.org/10.13039/501100000761 Leverhulme Trust http://dx.doi.org/10.13039/501100000275 RPG-2023-085...

... populations, tissue homeostasis and alleviating the consequences of aging. This Review highlights recent findings that illuminate how common diets and specific nutrients impact cell fate decisions in healthy and disease contexts. We also draw attention to new models, technologies and resources that help...

... in Neurog3 -null mutant mice, suggesting that Ascl1 might act via Neurog3 to drive VMH cell fate decisions. We also showed a concomitant increase in expression of the central GABAergic fate determinant Dlx1/2 in the Ascl1- null hypothalamus. However, Ascl1 was not sufficient to induce an ectopic VMH fate...

... mosaic expression of wild-type or mutant histone H3.3 variants provides insights into the function of specific histone residues during oogenesis and early development. Histone H3.3 Genetic mosaics Cell fate decision Protamine-to-histone exchange National Institute of Diabetes...

... that apicobasal divisions do not play a part in cell fate decisions, but instead control the position of progenitors in the neuroepithelium ( Konno et al., 2008 ; Morin et al., 2007 ), which was later proposed to control the balance between direct and indirect neurogenesis in the developing neocortex...

... that the original work is properly attributed. Highlighted article: Quantitative measurements and mathematical modeling reveal the integration of transcription factor activity and extracellular signaling during fate decisions in ESCs. Embryonic stem cells GATA factor Cell fate decision Dynamic...

...Benjamin Pfeuty Proper tissue development requires that stem/progenitor cells precisely coordinate cell division and differentiation in space and time. Notch-Hes1 intercellular signaling, which affects both differentiation and cell cycle progression and directs cell fate decisions at various...