..., with marginal cells proliferating faster than inner cells. A mathematical model suggests that stochastic variation in cell division, combined with strong inhibitory signals from dividing marginal cells, is sufficient to explain gametophyte dynamics. Experimental disruption of division timing agreed...

... cells. Stem cells Drosophila Signaling Cell division National Institute of General Medical Sciences R35 GM136270 T32GM008216 University of Pennsylvania http://dx.doi.org/10.13039/100006920 Stem cells are essential in supporting and repairing the tissues...

... at the mitotic spindle to ensure proper cell division. Furthermore, miR-31-mediated post-transcriptional regulation at the mitotic spindle may be an evolutionarily conserved regulatory paradigm of mitosis. * These authors contributed equally to this work ‡ Author for correspondence ( [email protected]...

... COTYLEDON3 regulates postembryonic shoot meristem and organ boundary formation . Plant Cell 18 , 2946 - 2957 . 10.1105/tpc.106.045716 Hussey , G. ( 1971 ). Cell division and expansion and resultant tissue 3 . J. Exp. Bot. 22 , 702 - 714 . 10.1093/jxb/22.3.702 Johnston...

... conditions, and can also detect other cellular events, such as cell division or cell differentiation. It also performs well on other epithelial tissues with reasonable re-training. Our methodology could easily be applied for other cellular events detected by live fluorescent microscopy and could help...

... with cell division angle but not with meristem positioning/size or AN3 localisation. In contrast, different shapes between sepals and petals compared with foliage leaves were associated with both altered meristem position, due to altered AN3 expression patterns, and different distributions of cell division...

... that zebrafish ( Danio rerio ) embryos lacking either maternal or paternal Cfap53, a centriolar satellite protein, arrest during the first cell cycle. Although Cfap53 is dispensable for sperm aster function, it aids proper formation of the mitotic spindle. During cell division, Cfap53 colocalizes with γ-tubulin...

...Timon W. Matz; Yang Wang; Ritika Kulshreshtha; Arun Sampathkumar; Zoran Nikoloski ABSTRACT Cell division and the resulting changes to the cell organization affect the shape and functionality of all tissues. Thus, understanding the determinants of the tissue-wide changes imposed by cell division...

... used fluorescence loss in photobleaching (FLIP) imaging to show that human embryonic stem cell (hESC)- and induced pluripotent stem cell (iPSC)-derived neural progenitor cells establish an ER diffusion barrier during cell division. The human ER diffusion barrier is regulated via lamin-dependent...

... expression at the shoot apical meristem ( Brand et al., 2002 ) likely excludes it as the ligand responsible for RPK2-mediated control of proximal branching. Another factor involved in the regulation of procambial cell division in embryonic cotyledons is the plasma membrane-associated protein OPS...

.... , Weijers , D. , Mulder , B. and Scheres , B. ( 2018 ). A plausible microtubule-based mechanism for cell division orientation in plant embryogenesis . Curr. Biol. 28 , 3031 - 3043.e3032 . 10.1016/j.cub.2018.07.025 Chory , J. , Nagpal , P. and Peto , C. A. ( 1991...

... thickening of the epithelium in the diastema anterior to the first developing molar is an early signaling center, the molar initiation knot (IK), which is required for the progression of mammalian molar tooth development. Cell division Migration Embryonic development Tooth Signaling center Wnt...

...Annika K. Weimer; Juliana L. Matos; Nidhi Sharma; Farah Patell; James A. H. Murray; Walter Dewitte; Dominique C. Bergmann ABSTRACT Plants, with cells fixed in place by rigid walls, often utilize spatial and temporally distinct cell division programs to organize and maintain organs. This leads...

... by increasing cell numbers through DNA synthesis and mitosis. Cell division Ecdysone Growth Imaginal disk Insulin Tissue culture National Science Foundation 10.13039/100000001 IOS-064114 IOS-0744952 IOS-1557341 Growth can be due to an increase in cell number, or an increase...

... throughout segmentation. Our data are complemented by cell division profiles and expression patterns of key genes, including invected and even-skipped as markers for different stages of segment formation. We describe morphological and mechanistic changes in the growth zone and in nascent segments during...

...Dennis A. Ridenour; Rebecca McLennan; Jessica M. Teddy; Craig L. Semerad; Jeffrey S. Haug; Paul M. Kulesa Embryonic cells that migrate long distances must critically balance cell division in order to maintain stream dynamics and population of peripheral targets. Yet details of individual cell...

... motifs. For example, we found that the Myb motif learned by the classifier is crucial for CC activity, and the Myb TF acts in concert with two forkhead domain TFs and Polo kinase to regulate cardiac progenitor cell divisions. In addition, differential motif enrichment and cis-trans genetic studies...

... timings, suggesting that cell division may directly control transcription. However, using mutants with specific defects in cell cycle pathways that lead to abnormal lineages, we found that the order between cell divisions and expression onset can switch, showing that expression of developmental regulators...

... down their long axis in a highly ordered manner, parallel to the tangential axis of the stem. CLAVATA3-LIKE/ESR-RELATED 41 (CLE41) and PHLOEM INTERCALATED WITH XYLEM (PXY) are a multifunctional ligand-receptor pair that regulate vascular cell division, vascular organisation and xylem differentiation...

... capacity in animals, and the potential for differentiated melanocyte cell division in development and regeneration remains largely unexplored. Here, we use time-lapse imaging of the developing zebrafish to show that while most melanocytes arise from undifferentiated precursor cells, an unexpected...