... liver progenitors to functional hepatocytes requires anisotropic elongation of their nascent apical surfaces into tubular bile canaliculi. Bile canaliculi Cell differentiation Cell fate Cell polarity Liver development Rab35 Mouse European Molecular Biology Organization http...

... erythropoiesis PDGF Sclerotome ERK1/2 Cell differentiation National Natural Science Foundation of China http://dx.doi.org/10.13039/501100001809 32100659 31900989 32330029 32025014 Shantou University http://dx.doi.org/10.13039/100009047 NTF22025 Fundamental Research...

... medium provided that the original work is properly attributed. Summary: A longitudinal, mediolateral wave of symmetrical and asymmetrical cell divisions and a short-range gradient of cell differentiation initiates and reinforces 3D growth during brown alga embryogenesis, ensuring body thickening...

.... ( 2022 ). CHD7 regulates otic lineage specification and hair cell differentiation in human inner ear organoids . Nat. Commun. 13 , 7053 . 10.1038/s41467-022-34759-8 Nist-Lund , C. , Kim , J. and Koehler , K. R. ( 2022 ). Advancements in inner ear development, regeneration...

... and Sox10-Cre resulted in an absence of taste papillae at E12.0. Biochemical and cell differentiation analyses demonstrated that mesenchymal ALK3-BMP signaling governed the production of previously unappreciated secretory proteins, i.e. it suppressed those that inhibit and facilitated those that promote...

...-nuclei analysis identified regulatory genes of cell differentiation in poplar apex, establishing a comparison between a model annual herbaceous and a woody perennial plant species. Populus Vascular development scRNA-seq Developmental trajectory Shoot apex Cell differentiation U.S...

... in beige adipocyte differentiation, priming their early cell fate commitment but attenuating their thermogenic activation at mature stages. Beige adipocyte Cell differentiation Thermogenesis Transcription factor FOXP4 Ministry of Science and Technology of the People's Republic of China...

...Chieh-Hsiang Tan; Kerry Kornfeld ABSTRACT Sperm activation is a rapid and dramatic cell differentiation event that does not involve changes in transcription, and the signaling cascades that mediate this process have not been fully defined. zipt-7.1 encodes a zinc transporter, and zipt-7.1(lf...

... in development, cell differentiation and normal physiology in vertebrates, and we discuss the sequence elements defining their functions. We also summarize progress on the discovery of regulatory RNA sequence elements, as well as their molecular functions and interaction partners. * Author...

... Mouse Blastocyst Cell differentiation Highlighted Article: During primitive endoderm differentiation in mouse, ERK activation is regulated by NANOG, which induces the expression of both Fgf4 and Etv5 , providing intrinsic and extrinsic signals at the same time. © 2019. Published...

... transferred in seminal fluid, in which it can influence sperm success. Reproduction Sperm Cell differentiation Intercellular signaling Protease inhibitor Seminal fluid Caenorhabditis elegans National Institutes of Health R01-GM087705 R01-GM118860 T32-GM007464 Sexual...

... renewal. Cell differentiation Mouse Progenitor proliferation Taste bud Smoothened antagonist Genentech 10.13039/100004328 National Institutes of Health In mammals, the adult lingual epithelium can be categorized into non-taste and taste components. The majority...

... discusses evidence linking CTCF to the control of developmental processes in various cell and tissue types through 3D organization of the genome. Transcription Epigenetics Development Genome organization Cell differentiation National Institutes of Health 10.13039/100000002100000002...

... differentiation. microRNAs Gene regulatory networks Embryogenesis Cell differentiation European Research Council 10.13039/501100000781 FP7/2007-2013 GA-337161 Austrian Science Fund 10.13039/501100002428 F4323-B09 Boehringer Ingelheim 10.13039/100001003...

... arrest serves a dual role: it prevents progenitor self-renewal and it synchronizes cell division with developmental signals. Neural development Sensory organs Mitosis G2 arrest Cell differentiation The development of a functional nervous system requires precise coordination of self...

... suggest a role for HDG proteins in promoting cell differentiation. We also reveal a transcriptional network in which BBM and HDG1 regulate several common target genes, and where BBM/AIL and HDG regulate the expression of each other. Taken together, these results suggest opposite roles for AIL and HDG...

...Barry Denholm; Nan Hu; Teddy Fauquier; Xavier Caubit; Laurent Fasano; Helen Skaer The physiological activities of organs are underpinned by an interplay between the distinct cell types they contain. However, little is known about the genetic control of patterned cell differentiation during organ...

... interests. 18 1 2012 © 2012. Phloem Arabidopsis Cell differentiation The plant vasculature is a complex network that interconnects all plant organs. Within the vasculature, xylem and phloem cells are specialised for the transport of water and organic compounds...

... ) Competing interests statement 17 4 2010 © 2010. CARM1 (PRMT4) Mouse Gene deletion Cell differentiation Cell proliferation Lung pathology Gene expression profiling Pulmonary cell Alveolar Respiratory development Respiratory distress BASC...

... for correspondence ( [email protected] ) Competing interests statement The authors declare no competing financial interests. © 2010. 2010 Prox1 Cell differentiation Cell plasticity Endothelial cell Lymphatics Until recently, lineage commitment and differentiation into a mature...