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Keywords: Cell competition
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Journal Articles
Journal: Development
Development (2019) 146 (13): dev167486.
Published: 05 July 2019
...Sarah Bowling; Katerina Lawlor; Tristan A. Rodríguez ABSTRACT The process of cell competition results in the elimination of cells that are viable but ‘less fit’ than surrounding cells. Given the highly heterogeneous nature of our tissues, it seems increasingly likely that cells are engaged...
Journal Articles
Journal: Development
Development (2019) 146 (3): dev170753.
Published: 01 February 2019
... is essential for cardiomyocyte proliferation and cardiogenesis. Mosaic Myc overexpression in a Mycn -deficient background shows that Myc can replace Mycn function, recovering heart development. We further show that this recovery involves the elimination of Mycn-deficient cells by cell competition. Our results...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (2): dev167643.
Published: 29 January 2019
... and highlighting JAK/STAT pathway functions in proliferation, survival and cell competition that are conserved between Drosophila and vertebrates. JAK/STAT is one of a handful of conserved signal transduction pathways required for normal development and adult physiology, as well as for regenerative responses...
Journal Articles
Journal: Development
Development (2012) 139 (21): 4051–4061.
Published: 01 November 2012
...Aloma B. Rodrigues; Tamara Zoranovic; Aidee Ayala-Camargo; Savraj Grewal; Tamara Reyes-Robles; Michelle Krasny; D. Christine Wu; Laura A. Johnston; Erika A. Bach Cell competition is a conserved mechanism that regulates organ size and shares properties with the early stages of cancer. In Drosophila...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (15): 2663–2669.
Published: 01 August 2012
... - 2588 . Drosophila Hh Cell competition Somatic stem cell niche Testis Stem cells are specified and maintained by specific microenvironments called niches. The niches in the fly testis and ovary harbour germline stem cell (GSC) and somatic stem cell populations, the sizes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (22): 3747–3756.
Published: 15 November 2009
...Francisco A. Martín; Salvador C. Herrera; Ginés Morata We report here experiments aimed at understanding the connections between cell competition and growth in the Drosophila wing disc. The principal assay has been to generate discs containing marked cells that proliferate at different rates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (6): 995–1006.
Published: 15 March 2009
...Christa Rhiner; Begoña Díaz; Marta Portela; Juan F. Poyatos; Irene Fernández-Ruiz; Jesús M. López-Gay; Offer Gerlitz; Eduardo Moreno Cell competition is a short-range cell-cell interaction leading to the proliferation of winner cells at the expense of losers, although either cell type shows...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (18): 4143–4154.
Published: 15 September 2005
...-mail: jfnicola@pasteur.fr ) 11 7 2005 ©2005. 2005 Stem cell Hair follicle Morphogenesis Cell lineage Cell behavior Clonal analysis Mouse Temporally induced clones Apoptosis Anagen Cell competition Developmental strategy The hair follicle (HF) is a fascinating...