... synapse formation were revealed using a newly developed in vitro co-culture system for mouse astrocytes and neurons. Tripartite synapse Astrocyte Neuron Cell adhesion molecule Necl Glutamate transporter Japan Society for the Promotion of Science http://dx.doi.org/10.13039...

... myocardium. Contactin-2 (CNTN2), a member of the immunoglobulin superfamily of cell adhesion molecules (IgSF-CAMs), was previously identified as a marker of the VCS. Through differential transcriptional profiling, we discovered two additional highly enriched IgSF-CAMs in the VCS: NCAM-1 and ALCAM...

... cell adhesion molecule ( epcam ) and reduction of cadherin 2 expression in the leading part of the primordium. Co-injection of snail1b morpholino with snail1b mRNA prevents the initial delay in migration and restores normal expression of epcam and cadherin 2 . The delay in initiating primordium...

... ). No mutant has been described in which the motor axons prematurely defasciculate in the periphery. Even in embryos with severe reductions in the axonal levels of the homophilic cell adhesion molecule Fas II, motor nerves adhere to each other properly as they grow out into the periphery. We infer from...

...Masaki Sone; Emiko Suzuki; Mikio Hoshino; Dongmei Hou; Hiroshi Kuromi; Masaki Fukata; Shinya Kuroda; Kozo Kaibuchi; Yo-ichi Nabeshima; Chihiro Hama ABSTRACT A cell-adhesion molecule fasciclin 2 (FAS2), which is required for synaptic growth and still life (SIF), an activator of RAC, were found...

... of C-axons at the ventral midline To address whether interactions with the floor plate are necessary to modulate cell-adhesion molecule localization on C-axons at the ventral midline, we examined the expression of three proteins that are detected at different levels on pre-and postcommissural...

...Andrew W. Stoker; Bernhard Gehrig; Fawaz Haj; Boon-Huat Bay ABSTRACT Migrating embryonic growth cones require multiple, membrane-associated signalling molecules to monitor and respond to guidance cues. Here we present the first evidence that vertebrate cell adhesion molecule-like protein tyrosine...

... of California at San Francisco, San Francisco, CA 94143, USA 26 07 1993 © 1993 by Company of Biologists 1993 CD44 cell adhesion molecule hyaluronan mouse embryogenesis instructive epithelium The hyaluronan receptor, CD44, is an integral plasma membrane glycoprotein credited...

... 03 1992 © 1992 by Company of Biologists 1992 HNK-1 neural crest cell adhesion molecule enteric nervous system Glycosylation and sulphatation are important post-translational modifications of proteins serving essential roles in embryonic development ( Sorkin et al., 1984...

.... In culture, isolated mononuclear cytotrophoblasts aggregate and then fuse to form syncytia, recapitulating the in vivo process. In the present studies, we investigated the expression of the Ca 2+ -dependent cell adhesion molecule (CAM), E-cadherin, during the morphologic differentiation of trophoblastic...

...-cadherin Xenopus embryo mRNA injection cell adhesion molecule morphogenesis Cell adhesion molecules are thought to be important for the construction of the animal body not only as physical cement but also as regulators of morphogenesis ( Edelman, 1988 ). Although the functions of cell...

... 1988 cadherins cell adhesion molecule CAM calcium protein antibody Cells of dissociated animal tissues can assemble autonomously and reform the original tissue-like structures ( Moscona & Moscona, 1952 ; Townes & Holtfreter, 1955 ; Weiss & Taylor, 1960 ). In some...

... by a class of cell surface molecules known as cell adhesion molecules (CAMs). In the present report, we have investigated the occurrence of the well-characterized cell adhesion molecule cell-CAM 105 on the surface of rat pre- and periimplantation embryos of various stages. This was carried out by indirect...

... without a morphologically identifiable axon. The antigen 69Al has been purified and shown to be immunochemically closely related or identical to the LI antigen. 09 03 1987 © 1987 by Company of Biologists 1987 neural surface antigen cell adhesion molecule axon growth neurite-neurite...