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Keywords: Cdk1
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Journal Articles
Journal: Development
Development (2022) 149 (10): dev200351.
Published: 26 May 2022
... induced sustained activity of PLK1 when cells exhibited DNA lesions that inhibited CHK2 and upregulated the activation of CDK1, resulting in inefficient loading of the essential HR factor RAD51. On the other hand, when inhibiting PLK1 in the S phase, DNA end resection was restricted. These results...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2012) 139 (3): 547–557.
Published: 1 February 2012
.... Endocycle Cyclin A ORC2 Cdk1 Neural development Drosophila Endocycles arise from drastic modifications of the canonical G1-S-G2-M cell cycle that result in successive rounds of DNA replication without intervening mitoses, leading to polyploid cells. Multiple genomic copies...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (4): 697–709.
Published: 15 February 2006
... oocytes. † Author for correspondence (e-mail: andyg@intra.niddk.nih.gov ) * Present address: Department of Biology, College of William and Mary,Williamsburg, VA 23187, USA 7 12 2005 © 2006. 2006 Oocyte maturation Meiotic maturation Myt1 Wee1 Cdk1...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (1999) 126 (9): 1793–1803.
Published: 1 May 1999
...Dara A. Lehman; Briony Patterson; Laura A. Johnston; Tracy Balzer; Jessica S. Britton; Robert Saint; Bruce A. Edgar Mitosis in most Drosophila cells is triggered by brief bursts of transcription of string (stg) , a Cdc25-type phosphatase that activates the mitotic kinase, Cdk1 (Cdc2). To understand...