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Keywords: Cardiogenesis
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Journal Articles
Journal: Development
Development (2023) 150 (18): dev201707.
Published: 25 September 2023
... of myocardial progenitor cells at the embryonic midline to form the heart cone and then initiate leftward-directed heart tube elongation. Klf2 Wnt9 Cardiogenesis Zebrafish Morphogenesis During the formation of the nascent zebrafish heart tube, myocardial progenitor cells migrate from bilateral...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2018) 145 (24): dev171983.
Published: 20 December 2018
... transcription factors Cardiogenesis Epigenetic regulator Heart regeneration Heart disease, the leading cause of death worldwide, arises primarily from loss of or damage to cardiomyocytes – the muscle cells that generate the contractile force of the heart. Cardiomyocyte loss can occur in response...
Journal Articles
Journal: Development
Development (2018) 145 (7): dev152488.
Published: 29 March 2018
...Hinako Kidokoro; Sayuri Yonei-Tamura; Koji Tamura; Gary C. Schoenwolf; Yukio Saijoh ABSTRACT In the initiation of cardiogenesis, the heart primordia transform from bilateral flat sheets of mesoderm into an elongated midline tube. Here, we discover that this rapid architectural change is driven...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (5): 846–857.
Published: 1 March 2015
... analysis on single cardiac lineage cells provides a high-resolution view of cardiac fate choice in the mouse embryo and during stem cell differentiation. Cardiac progenitor cells Cardiogenesis Embryonic stem cell Nkx2-5 Differentiation The heart is the first organ to form during mouse...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (24): 5357–5368.
Published: 15 December 2011
... The authors declare no competing financial interests. 5 10 2011 © 2011. Cardiogenesis Flk1 (Kdr) Hemangioblasts Hematopoiesis VEGF Vasculogenesis Mouse Mesodermal cells give rise to blood, blood vessel, kidney, cardiac and skeletal muscle. These tissues...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (21): 4627–4638.
Published: 1 November 2011
...Aaron N. Johnson; Mayssa H. Mokalled; Tom N. Haden; Eric N. Olson Intercellular signal transduction pathways regulate the NK-2 family of transcription factors in a conserved gene regulatory network that directs cardiogenesis in both flies and mammals. The Drosophila NK-2 protein Tinman (Tin...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2010) 137 (18): 2989–3000.
Published: 15 September 2010
... blocks the FGF synexpression group. ( C , D ) In situ hybridization screen, in whole-mount and sectioned embryos, for the BMP4 (C) and FGF (D) synexpression groups at the indicated stages of cardiogenesis in the chick. Left, ventral view; middle, lateral view; right, transverse sections at the indicated...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (11): 1919–1929.
Published: 1 June 2010
..., USA Competing interests statement 6 4 2010 © 2010. Tbx20 Cardiogenesis Cardiac Heart Xenopus laevis Xenopus tropicalis SMAD1 SMAD4 T-box BMP Zebrafish Transgenesis A series of clinical studies has provided direct evidence...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (9): 1465–1474.
Published: 1 May 2009
...,and for the origins of stem cells in the adult heart. * Author for correspondence (e-mail: roger.patient@imm.ox.ac.uk ) 24 2 2009 © 2009. 2009 Myelopoiesis Cardiogenesis GATA factors Second heart field Haemangioblasts Transcriptional regulation Evolution Adult stem cells Zebrafish...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (2): 317–326.
Published: 15 January 2009
... inductive signals Dpp and Wg. Genetic interactions show that tup cooperates with tin, pnr and Doc in heart cell specification. Germ layer-specific loss-of-function and rescue experiments reveal that Tup also functions in the ectoderm to regulate cardiogenesis and implicate the involvement of different LIM...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2006) 133 (22): 4585–4593.
Published: 15 November 2006
...Kai Jiao; Melissa Langworthy; Lorene Batts; Chris B. Brown; Harold L. Moses; H. Scott Baldwin The transforming growth factorβ (Tgfβ) signaling pathway plays crucial roles in many biological processes. To understand the role(s) of Tgfβ signaling during cardiogenesis in vivo and to overcome the early...
Journal Articles
Journal: Development
Development (2006) 133 (13): 2575–2584.
Published: 1 July 2006
... microscope. * Author for correspondence (e-mail: frank_conlon@med.unc.edu ) 28 4 2006 © 2006. 2006 Tbx5 Holt-Oram Syndrome Cardiogenesis Cardiac Heart Xenopus Cell cycle S-phase Proliferation T-box Hyperplastic growth of the vertebrate heart...
Journal Articles
Journal: Development
Development (2006) 133 (12): 2435–2445.
Published: 15 June 2006
... field (AHF),which we use to describe specifically the SM and CM that contribute to the myocardium of the OT and RV. Fgf8 Anterior heart field Cardiogenesis Cell Survival Proliferation Pea3 Bmp4 Erk Mouse © 2006. 2006 18 4 2006 * Author...
Journal Articles
Journal: Development
Development (2006) 133 (6): 1175–1182.
Published: 15 March 2006
... the lethality of Hand mutants, and cardiac expression of a human HAND gene, or the caspase inhibitor P35,partially rescued the cardiac and lymph gland phenotypes. These findings demonstrate evolutionarily conserved functions of HAND transcription factors in Drosophila and mammalian cardiogenesis, and reveal...
Journal Articles
Journal Articles
Journal: Development
Development (2005) 132 (3): 553–563.
Published: 1 February 2005
... interaction between members of the T-box gene family. * Author for correspondence (e-mail: frank_conlon@med.unc.edu ) 23 11 2004 ©2005. 2005 Tbx5 Tbx20 T-Box T-domain Cardiogenesis Cardiac Heart Development Xenopus laevis The vertebrate heart constitutes...
Includes: Supplementary data
Journal Articles