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1-20 of 44
Keywords: Cardiogenesis
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Journal Articles
In collection:
Cardiovascular development and regeneration
Journal:
Development
Development (2023) 150 (18): dev201707.
Published: 25 September 2023
... of myocardial progenitor cells at the embryonic midline to form the heart cone and then initiate leftward-directed heart tube elongation. Klf2 Wnt9 Cardiogenesis Zebrafish Morphogenesis During the formation of the nascent zebrafish heart tube, myocardial progenitor cells migrate from bilateral...
Includes: Supplementary data
Journal Articles
In collection:
Cardiovascular development and regeneration
Rajani M. George, Beth A. Firulli, Ram Podicheti, Douglas B. Rusch, Brandon J. Mannion, Len A. Pennacchio, Marco Osterwalder, Anthony B. Firulli
Journal:
Development
Development (2023) 150 (3): dev201341.
Published: 6 February 2023
...Rajani M. George; Beth A. Firulli; Ram Podicheti; Douglas B. Rusch; Brandon J. Mannion; Len A. Pennacchio; Marco Osterwalder; Anthony B. Firulli ABSTRACT The transcription factor HAND2 plays essential roles during cardiogenesis. Hand2 endocardial deletion ( H2CKO ) results in tricuspid atresia...
Includes: Supplementary data
Journal Articles
In collection:
Cardiovascular development and regeneration
,
Chromatin and epigenetics
,
Stem cells & regeneration
Journal:
Development
Development (2018) 145 (24): dev171983.
Published: 20 December 2018
... remodeling Cardiac transcription factors Cardiogenesis Epigenetic regulator Heart regeneration National Institutes of Health 10.13039/100000002 AR-067294 Fondation Leducq 10.13039/501100001674 Welch Foundation 10.13039/100000928 1-0025 Heart disease...
Journal Articles
In collection:
Cardiovascular development and regeneration
Journal:
Development
Development (2018) 145 (7): dev152488.
Published: 29 March 2018
...Hinako Kidokoro; Sayuri Yonei-Tamura; Koji Tamura; Gary C. Schoenwolf; Yukio Saijoh ABSTRACT In the initiation of cardiogenesis, the heart primordia transform from bilateral flat sheets of mesoderm into an elongated midline tube. Here, we discover that this rapid architectural change is driven...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2016) 143 (2): 306–317.
Published: 15 January 2016
...Shaad M. Ahmad; Pritha Bhattacharyya; Neal Jeffries; Stephen S. Gisselbrecht; Alan M. Michelson Cardiogenesis involves the coordinated regulation of multiple biological processes by a finite set of transcription factors (TFs). Here, we show that the Forkhead TFs Checkpoint suppressor homologue...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells & regeneration
Journal:
Development
Development (2015) 142 (5): 846–857.
Published: 1 March 2015
... analysis on single cardiac lineage cells provides a high-resolution view of cardiac fate choice in the mouse embryo and during stem cell differentiation. Cardiac progenitor cells Cardiogenesis Embryonic stem cell Nkx2-5 Differentiation The heart is the first organ to form during mouse...
Includes: Supplementary data
Journal Articles
Hiroyuki Ishitobi, Asami Wakamatsu, Fang Liu, Takuya Azami, Michito Hamada, Ken Matsumoto, Hiroshi Kataoka, Makoto Kobayashi, Kyunghee Choi, Shin-ichi Nishikawa, Satoru Takahashi, Masatsugu Ema
Journal:
Development
Development (2011) 138 (24): 5357–5368.
Published: 15 December 2011
... The authors declare no competing financial interests. 5 10 2011 © 2011. Cardiogenesis Flk1 (Kdr) Hemangioblasts Hematopoiesis VEGF Vasculogenesis Mouse Mesodermal cells give rise to blood, blood vessel, kidney, cardiac and skeletal muscle. These tissues...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2011) 138 (21): 4627–4638.
Published: 1 November 2011
...Aaron N. Johnson; Mayssa H. Mokalled; Tom N. Haden; Eric N. Olson Intercellular signal transduction pathways regulate the NK-2 family of transcription factors in a conserved gene regulatory network that directs cardiogenesis in both flies and mammals. The Drosophila NK-2 protein Tinman (Tin...
Includes: Supplementary data
Journal Articles
Pari-Sima Müller, Ramona Schulz, Silvia Maretto, Ita Costello, Shankar Srinivas, Elizabeth Bikoff, Elizabeth Robertson
Journal:
Development
Development (2011) 138 (7): 1297–1308.
Published: 1 April 2011
... cardiogenesis . Proc. Natl. Acad. Sci. USA 101 , 12573 - 12578 . Wheldon L. M. , Haines B. P. , Rajappa R. , Mason I. , Rigby P. W. , Heath J. K. ( 2010 ). Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor...
Includes: Supplementary data
Journal Articles
Libbat Tirosh-Finkel, Amit Zeisel, Miriam Brodt-Ivenshitz, Ayelet Shamai, Zhong Yao, Rony Seger, Eytan Domany, Eldad Tzahor
Journal:
Development
Development (2010) 137 (18): 2989–3000.
Published: 15 September 2010
... blocks the FGF synexpression group. ( C , D ) In situ hybridization screen, in whole-mount and sectioned embryos, for the BMP4 (C) and FGF (D) synexpression groups at the indicated stages of cardiogenesis in the chick. Left, ventral view; middle, lateral view; right, transverse sections at the indicated...
Includes: Supplementary data
Journal Articles
Elizabeth M. Mandel, Erin Kaltenbrun, Thomas E. Callis, Xin-Xin I. Zeng, Sara R. Marques, Deborah Yelon, Da-Zhi Wang, Frank L. Conlon
Journal:
Development
Development (2010) 137 (11): 1919–1929.
Published: 1 June 2010
..., USA Competing interests statement 6 4 2010 © 2010. Tbx20 Cardiogenesis Cardiac Heart Xenopus laevis Xenopus tropicalis SMAD1 SMAD4 T-box BMP Zebrafish Transgenesis A series of clinical studies has provided direct evidence...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2009) 136 (9): 1465–1474.
Published: 1 May 2009
...,and for the origins of stem cells in the adult heart. * Author for correspondence (e-mail: [email protected] ) 24 2 2009 © 2009. 2009 Myelopoiesis Cardiogenesis GATA factors Second heart field Haemangioblasts Transcriptional regulation Evolution Adult stem cells Zebrafish...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2009) 136 (2): 317–326.
Published: 15 January 2009
... inductive signals Dpp and Wg. Genetic interactions show that tup cooperates with tin, pnr and Doc in heart cell specification. Germ layer-specific loss-of-function and rescue experiments reveal that Tup also functions in the ectoderm to regulate cardiogenesis and implicate the involvement of different LIM...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2006) 133 (22): 4585–4593.
Published: 15 November 2006
...Kai Jiao; Melissa Langworthy; Lorene Batts; Chris B. Brown; Harold L. Moses; H. Scott Baldwin The transforming growth factorβ (Tgfβ) signaling pathway plays crucial roles in many biological processes. To understand the role(s) of Tgfβ signaling during cardiogenesis in vivo and to overcome the early...
Journal Articles
Journal:
Development
Development (2006) 133 (13): 2575–2584.
Published: 1 July 2006
... microscope. * Author for correspondence (e-mail: [email protected] ) 28 4 2006 © 2006. 2006 Tbx5 Holt-Oram Syndrome Cardiogenesis Cardiac Heart Xenopus Cell cycle S-phase Proliferation T-box Hyperplastic growth of the vertebrate heart...
Journal Articles
Roger Ilagan, Radwan Abu-Issa, Doris Brown, Yu-Ping Yang, Kai Jiao, Robert J. Schwartz, John Klingensmith, Erik N. Meyers
Journal:
Development
Development (2006) 133 (12): 2435–2445.
Published: 15 June 2006
... field (AHF),which we use to describe specifically the SM and CM that contribute to the myocardium of the OT and RV. Fgf8 Anterior heart field Cardiogenesis Cell Survival Proliferation Pea3 Bmp4 Erk Mouse © 2006. 2006 18 4 2006 * Author...
Journal Articles
Journal:
Development
Development (2006) 133 (6): 1175–1182.
Published: 15 March 2006
... the lethality of Hand mutants, and cardiac expression of a human HAND gene, or the caspase inhibitor P35,partially rescued the cardiac and lymph gland phenotypes. These findings demonstrate evolutionarily conserved functions of HAND transcription factors in Drosophila and mammalian cardiogenesis, and reveal...
Journal Articles
Dillon Phan, Tara L. Rasmussen, Osamu Nakagawa, John McAnally, Paul D. Gottlieb, Philip W. Tucker, James A. Richardson, Rhonda Bassel-Duby, Eric N. Olson
Journal:
Development
Development (2005) 132 (11): 2669–2678.
Published: 1 June 2005
... expression MEF2 binding site E-box Cardiogenesis Mouse Anterior heart field Heart development is a precisely orchestrated process in which even subtle perturbations can have catastrophic consequences for the organism (reviewed by Fishman and Olson, 1997 ). During vertebrate embryogenesis, heart...
Journal Articles
Daniel D. Brown, Shauna N. Martz, Olav Binder, Sarah C. Goetz, Brenda M. J. Price, Jim C. Smith, Frank L. Conlon
Journal:
Development
Development (2005) 132 (3): 553–563.
Published: 1 February 2005
... interaction between members of the T-box gene family. * Author for correspondence (e-mail: [email protected] ) 23 11 2004 ©2005. 2005 Tbx5 Tbx20 T-Box T-domain Cardiogenesis Cardiac Heart Development Xenopus laevis The vertebrate heart constitutes...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2004) 131 (19): 4709–4723.
Published: 1 October 2004
... 2004. 2004 Nkx2.5 BMP YY1 GATA SMADs Cardiogenesis Chick The heart is the first organ to develop during vertebrate embryogenesis and arises from cardiac progenitor cells that migrate into the anterior lateral mesoderm during gastrulation ( DeHaan,1965 ; Rawles,1943 ; Rosenquist...
Includes: Supplementary data
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