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Keywords: Cardiac valve development
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Journal Articles

Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve

In collection:
Cardiovascular development and regeneration
David Bassen, Mingkun Wang, Duc Pham, Shuofei Sun, Rashmi Rao, Rishabh Singh, Jonathan Butcher
Journal: Development
Development (2021) 148 (13): dev196519.
https://doi.org/10.1242/dev.196519
Published: 1 July 2021
... regulates valve development through a molecular switch potentiating BMP-pSMAD1/5-driven growth and pSer-19-MLC2-driven contractility. Mechanobiology Cardiac valve development BMP signaling MLC contractility Congenital heart defects (CHDs) are the most common birth defects and the leading...
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Includes: Supplementary data
Journal Articles

A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme

In collection:
Cardiovascular development and regeneration
Kuo Liu, Wei Yu, Muxue Tang, Juan Tang, Xiuxiu Liu, Qiaozhen Liu, Yan Li, Lingjuan He, Libo Zhang, Sylvia M. Evans, Xueying Tian, Kathy O. Lui, Bin Zhou
Journal: Development
Development (2018) 145 (18): dev167775.
https://doi.org/10.1242/dev.167775
Published: 17 September 2018
... engineering Site-specific recombinase (SSR) Nigri-nox Fate mapping Cardiac valve development National Key Research and Development Program of China 2016YFC1300600 2017YFC1001303 2018YFA0107900 2018YFA0108100 Chinese Academy of Sciences 10.13039/501100002367 XDB19000000...
View article titled, A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme
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Includes: Supplementary data