...Natalie Gibb; Savo Lazic; Xuefei Yuan; Ashish R. Deshwar; Meaghan Leslie; Michael D. Wilson; Ian C. Scott ABSTRACT A key event in heart development is the timely addition of cardiac progenitor cells, defects in which can lead to congenital heart defects. However, how the balance and proportion...

...Noelle Paffett-Lugassy; Natasha Novikov; Spencer Jeffrey; Maryline Abrial; Burcu Guner-Ataman; Srinivasan Sakthivel; Caroline E. Burns; C. Geoffrey Burns During mammalian embryogenesis, cardiac progenitor cells constituting the second heart field (SHF) give rise to the right ventricle and primitive...

... © 2011. 2011 Bmp signaling Cardiac arterial pole Cardiac progenitors Hedgehog signaling Second heart field tbx1 Zebrafish In chick and mouse, cardiac progenitors are organized bilaterally in the epiblast on either side of the primitive streak ( Hatada and Stern, 1994 ; Tam et...

...Qiaoyun Yue; Laura Wagstaff; Xuesong Yang; Cornelis Weijer; Andrea Münsterberg The heart is the first organ to function during vertebrate development and cardiac progenitors are among the first cell lineages to be established. In the chick, cardiac progenitors have been mapped in the epiblast...

...Didier Y. R. Stainier; Robert K. Lee; Mark C. Fishman ABSTRACT We have analyzed the origin of cardiac progenitors in the zebrafish embryo by injection of single blastomeres with a lineage tracer dye, and examined the formation of the zebrafish heart tube by serial sectioning of immunostained...