...Gina Broitman-Maduro; Simo Sun; Taisei Kikuchi; Morris F. Maduro ABSTRACT Endoderm specification in Caenorhabditis elegans occurs through a network in which maternally provided SKN-1/Nrf, with additional input from POP-1/TCF, activates the GATA factor cascade MED-1,2→END-1,3→ELT-2,7. Orthologues...

... and progression. Germline Reproductive aging Caenorhabditis Stem cells Notch Cell cycle Endomitotic oocytes Meiotic development Fig. 1. The female reproductive system displays rapid age-related decline in sperm-replete C. elegans. (A) Number of progeny produced in 24 h intervals...

... regulated spermatogenesis in an otherwise female body. The PUF family RNA-binding proteins FBF-1 and FBF-2 limit XX spermatogenesis by repressing the male-promoting proteins FEM-3 and GLD-1. Here, we examine the function of PUF homologs from other Caenorhabditis species, with emphasis on C. briggsae , which...

...Florence Solari; Alex Bateman; Julie Ahringer ABSTRACT We show here that two functionally redundant Caenorhabditis elegans genes, egl-27 and egr-1 , have a fundamental role in embryonic patterning. When both are inactivated, cells in essentially all regions of the embryo fail to be properly...

...Anne Duggan; Charles Ma; Martin Chalfie ABSTRACT The nematode Caenorhabditis elegans possesses six morphologically similar neurons that are responsible for sensing gentle touch to the body. Previous genetic studies identified genes that are necessary for the production and differentiation...

...Rebecca D. Burdine; Catherine S. Branda; Michael J. Stern ABSTRACT During the development of the egg-laying system in Caenorhabditis elegans hermaphrodites, central gonadal cells organize the alignment of the vulva with the sex myoblasts, the progenitors of the egg-laying muscles. A fibroblast...

... forms of DSL ligands in other systems may be created. * Author for correspondence (e-mail: [email protected] ) 13 09 1995 © 1995 by Company of Biologists 1995 Delta lag-2 lin-12 Notch glp-1 ligand Caenorhabditis During animal development...

... Hox genes homeotic genes mab-21 Caenorhabditis neurogenesis cell signalling During animal development, pattern-formation mechanisms guide the generation of variant forms of a variety of serially repeated structures, such as segments, rhombomeres, digits or sensory organs. One way...

... symmetrical intestinal valve cells during embryogenesis in Caenorhabditis elegans . Development 116 , 1113 – 1122 . Bowerman , B. , Draper , B. W. , Mello , C. C. and Priess , J. R. ( 1993 ). The maternal gene skn-1 encodes a protein that is distributed unequally in early...

...Anna P. Newman; John G. White; Paul W. Sternberg ABSTRACT The anchor cell (AC) of the Caenorhabditis elegans gonad has a critical role in the development of a functional egglaying system, which is accomplished through cell-cell interactions. Lateral inhibitory lin-12 -mediated signaling among two...

...Lois G. Edgar; Nurit Wolf; William B. Wood ABSTRACT We have analysed early transcription in devitellinized, cultured embryos of the nematode Caenorhabditis elegans by two methods: measurement of [ 32 P]UTP uptake into TCA-precipitable material and autoradiographic detection of [ 3 H]UTP labelling...

... of Caenorhabditis elegans . Genetics 77 , 71 – 94 . 10.1093/genetics/77.1.71 Chitwood , B. G. & Chitwood , M. B. ( 1974 ). Introduction to Nematology . Baltimore : University Park Press . Cowan , A. E. & Mcintosh , J. R. ( 1985 ). Mapping the distribution...