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Keywords: Cadherins
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Journal Articles
Journal: Development
Development (2022) 149 (15): dev200712.
Published: 29 July 2022
... driving their epithelial-to-mesenchymal transition. Neural crest EMT Morphogens Cadherins Transcription factors Post-translational modifications School of Veterinary Medicine, University of California, Davis http://dx.doi.org/10.13039/100009751 National Science Foundation...
Journal Articles
In collection:
Neural development
Journal: Development
Development (2017) 144 (5): 830–836.
Published: 1 March 2017
... of organisation are largely unknown. We have previously shown that the assembly of motor neurons into nuclei depends on cadherin-mediated adhesion. Here, we demonstrate that the emergence of mature topography among motor nuclei involves a novel interplay between spontaneous activity, cadherin expression and gap...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (10): 2099–2109.
Published: 15 May 2011
... that absence of the cadherin regulator p120 catenin (p120ctn) from the renal mesenchyme prior to tubule formation leads to decreased cadherin levels with abnormal morphologies of early tubule structures and developing glomeruli. In addition, mutant mice develop cystic kidney disease, with markedly increased...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (20): 3477–3487.
Published: 15 October 2010
... maturation of epithelial rosettes in the pLLp. In addition, atoh1a inhibits e-cadherin expression, which is likely to reduce cohesion and contribute to fragmentation of the pLLp. Together, our observations reveal a genetic regulatory network that explains why atoh1a expression must be restricted by Notch...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (14): 2297–2305.
Published: 15 July 2010
...Lenka Libusova; Marc P. Stemmler; Andreas Hierholzer; Heinz Schwarz; Rolf Kemler We conditionally substituted E-cadherin (E-cad; cadherin 1) with N-cadherin (N-cad; cadherin 2) during intestine development by generating mice in which an Ncad cDNA was knocked into the Ecad locus. Mutant mice were...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (5): 805–814.
Published: 1 March 2010
...Sarah H. Barnes; Stephen R. Price; Corinna Wentzel; Sarah C. Guthrie Cadherin-7 (Cad7) and cadherin-6B (Cad6B) are expressed in early and late phases of cranial motoneuron development, respectively. Cad7 is expressed by cranial motoneurons soon after they are generated, as well...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (24): 4155–4164.
Published: 15 December 2009
... for the cell adhesion molecule N-cadherin and its interaction with Slit1-Robo2 during gangliogenesis in vivo. A common feature of chick trigeminal and epibranchial ganglia is the expression of N-cadherin and Robo2 on placodal neurons and Slit1 on neural crest cells. Interestingly, N-cadherin localizes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (14): 2651–2661.
Published: 15 July 2007
... by signaling through G-protein-coupled receptors. In this paper, we show that the cortical actin network colocalizes with foci of cadherin expressed on the cell surface. We then show that cell-surface cadherin expression is both necessary and sufficient for cortical actin assembly and requires the associated...
Journal Articles
Journal: Development
Development (2006) 133 (17): 3283–3293.
Published: 1 September 2006
... unknown. Here, we demonstrate that the Drosophila DE- and DN-cadherins have opposing effects on rotation. DE-cadherin promotes rotation, as DE-cad mutant ommatidia rotate less than wild type or not at all. By contrast, the two DN-cadherins act to restrict this movement, with ommatidia rotating too fast...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (24): 6175–6184.
Published: 15 December 2004
... on the Drosophila eye, we proposed that a crucial step in this process is the establishment of graded expression of the cadherin Dachsous (Ds) and the Golgi-associated protein Four-jointed (Fj). These gradients were proposed to specify the direction of polarization by producing an activity gradient of the cadherin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (4): 881–890.
Published: 15 February 2004
... were assayed for function in vivo. We find that cleavage and secretion of Fj is not necessary for activity,and that Golgi-anchored Fj has increased activity over wild type. fj has similar phenotypes to those caused by mutations in the cadherin-encoding genes fat ( ft ) and dachsous ( ds ). We show...