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Keywords: CREB
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Journal Articles

G protein-coupled receptor 48 upregulates estrogen receptor α expression via cAMP/PKA signaling in the male reproductive tract

Xiao-Ying Li, Yan Lu, Hai-Yan Sun, Ji-Qiu Wang, Jun Yang, Hui-Jie Zhang, Neng-Guang Fan, Jia Xu, Jing-Jing Jiang, Ru-Ya Liu, Da-Li Li, Ming-Yao Liu, Guang Ning
Journal: Development
Development (2010) 137 (1): 151–157.
https://doi.org/10.1242/dev.040659
Published: 1 January 2010
... be upregulated by Gpr48 activation via the cAMP/PKA signaling pathway. Moreover, we identified a cAMP responsive element ( Cre ) motif located at −1307 to −1300 bp in the ER α promoter that is able to interact with Cre binding protein (Creb). In conclusion, Gpr48 participates in the development of the male...
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Includes: Supplementary data
Journal Articles

Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis

Rosanna Parlato, Christiane Otto, Yvonne Begus, Stephanie Stotz, Günther Schütz
Journal: Development
Development (2007) 134 (9): 1663–1670.
https://doi.org/10.1242/dev.02838
Published: 1 May 2007
...Rosanna Parlato; Christiane Otto; Yvonne Begus; Stephanie Stotz; Günther Schütz The cyclic-AMP response element-binding (CREB) protein family of transcription factors plays a crucial role in supporting the survival of neurons. However, a cell-autonomous role has not been addressed in vivo...
View article titled, Specific ablation of the transcription factor <span class="search-highlight">CREB</span> in sympathetic neurons surprisingly protects against developmentally regulated apoptosis
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Journal Articles

Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage and survival of hematopoietic progenitors

Melinda J. Walters, Gary A. Wayman, John C. Notis, Richard H. Goodman, Thomas R. Soderling, Jan L. Christian
Journal: Development
Development (2002) 129 (6): 1455–1466.
https://doi.org/10.1242/dev.129.6.1455
Published: 15 March 2002
... of receptor activation. Our data are consistent with a model in which CaM KIV inhibits BMP signals by activating a substrate, possibly cAMP-response element-binding protein (CREB), that recruits limiting amounts of CREB binding protein (CBP) away from transcriptional complexes functioning downstream of BMPs...
View article titled, Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage and survival of hematopoietic progenitors
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Journal Articles

The CREB family of activators is required for endochondral bone development

Fanxin Long, Ernestina Schipani, Hiroshi Asahara, Henry Kronenberg, Marc Montminy
Journal: Development
Development (2001) 128 (4): 541–550.
https://doi.org/10.1242/dev.128.4.541
Published: 15 February 2001
...Fanxin Long; Ernestina Schipani; Hiroshi Asahara; Henry Kronenberg; Marc Montminy We have evaluated the importance of the CREB family of transcriptional activators for endochondral bone formation by expressing a potent dominant negative CREB inhibitor (A-CREB) in growth plate chondrocytes...
View article titled, The <span class="search-highlight">CREB</span> family of activators is required for endochondral bone development
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