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Keywords: CLEC7A
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Journal Articles

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C

In collection:
Neural development
Bridget R. Boyle, Sierra E. Melli, Ruth S. Altreche, Zachary M. Padron, Fawad A. K. Yousufzai, Sarah Kim, Mariella D. Vasquez, Dawn M. Carone, Benjamin R. Carone, Ileana Soto
Journal: Development
Development (2020) 147 (21): dev189019.
https://doi.org/10.1242/dev.189019
Published: 3 August 2020
... attributed. Summary: Genetic deficiency of Npc1 impairs postnatal development of microglia and climbing fiber synaptic pruning in the mouse cerebellum. Cerebellum CLEC7A NPC VGLUT2 Microglia Pruning Niemann–Pick disease type C (NPC) is a recessive genetic lysosomal storage...
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Includes: Supplementary data