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Keywords: CHK2
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Journal Articles
Journal: Development
Development (2020) 147 (9): dev186171.
Published: 13 May 2020
... by inactivation of the ATR and Chk2 kinases. These data suggest that, similar to emerin/otefin mutants, BAF depletion activates the NL checkpoint that causes germ cell loss. Taken together, our findings provide evidence for a prominent NL partnership between the LEM-D protein Emerin/Otefin and BAF, revealing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (23): 4312–4323.
Published: 1 December 2016
.../ Highlighted article: DNA damage disrupts stem cell self-renewal and differentiation in a CHK2 kinase-dependent manner, which may be due to reduced BMP signaling and cell adhesion in the Drosophila ovary. CHK2 Differentiation Germline stem cell Lok Niche Self-renewal Stowers Institute...
Includes: Supplementary data