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Keywords: CBFA2T
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Journal Articles

Co-option of the PRDM14-CBFA2T complex from motor neurons to pluripotent cells during vertebrate evolution

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Masanori Kawaguchi, Kota Sugiyama, Kazumi Matsubara, Che-Yi Lin, Shigehiro Kuraku, Shota Hashimoto, Yoshiaki Suwa, Luok Wen Yong, Koji Takino, Shota Higashida, Daisuke Kawamura, Jr-Kai Yu, Yoshiyuki Seki
Journal: Development
Development (2019) 146 (2): dev168633.
https://doi.org/10.1242/dev.168633
Published: 28 January 2019
... function in maintaining mouse ESC pluripotency. Interestingly, sea urchin PRDM14 together with sea urchin CBFA2T, an essential partner of PRDM14 in mouse ESCs, complemented the self-renewal defect in mouse Prdm14 KO ESCs. Contrary to the Prdm14 expression pattern in mouse embryos, Prdm14 was expressed...
View article titled, Co-option of the PRDM14-CBFA2T complex from motor neurons to pluripotent cells during vertebrate evolution
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Includes: Supplementary data