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1-7 of 7
Keywords: Breast cancer
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Journal Articles
Loss of STING impairs lactogenic differentiation
Open AccessRamiah R. Vickers, Garhett L. Wyatt, Lilia Sanchez, Jordyn J. VanPortfliet, A. Phillip West, Weston W. Porter
Journal:
Development
Development (2024) 151 (19): dev202998.
Published: 14 October 2024
.... These findings affirm unique development of mammary gland pairs that is essential to consider in future investigations into normal development and breast cancer initiation. * Author for correspondence ( [email protected] ) Handling Editor: Liz Robertson Competing interests The authors declare...
Includes: Supplementary data
Journal Articles
Podoplanin regulates mammary stem cell function and tumorigenesis by potentiating Wnt/β-catenin signaling
Available to PurchaseLaura Bresson, Marisa M. Faraldo, Amandine Di-Cicco, Miguel Quintanilla, Marina A. Glukhova, Marie-Ange Deugnier
Journal:
Development
Development (2018) 145 (4): dev160382.
Published: 21 February 2018
... to be at the origin of certain breast cancers; however, the molecular identity of SCs and the factors regulating their function remain poorly defined. We identified the transmembrane protein podoplanin (Pdpn) as a specific marker of the basal compartment, including multipotent SCs, and found Pdpn localized...
Includes: Supplementary data
Journal Articles
Epithelial vimentin plays a functional role in mammary gland development
Available to Purchase
Journal:
Development
Development (2017) 144 (22): 4103–4113.
Published: 15 November 2017
... of basal MMECs reveals that lack of vimentin alters multiple pathways, including adhesion, cancer and Wnt signalling. Furthermore, vimentin contributes to stem-like cell properties in MDA-MB-231 breast cancer cells, wherein vimentin depletion reduces tumoursphere formation and attenuates expression...
Includes: Supplementary data
Journal Articles
Developmental stratification of the mammary epithelium occurs through symmetry-breaking vertical divisions of apically positioned luminal cells
Available to Purchase
Journal:
Development
Development (2014) 141 (5): 1085–1094.
Published: 1 March 2014
... . Hennighausen L. , Robinson G. W. ( 2005 ). Information networks in the mammary gland . Nat. Rev. Mol. Cell Biol. 6 , 715 – 725 . Hinck L. , Silberstein G. B. ( 2005 ). Key stages in mammary gland development: the mammary end bud as a motile organ . Breast Cancer Res. 7...
Journal Articles
ID4 regulates mammary gland development by suppressing p38MAPK activity
Available to PurchaseJie Dong, Shixia Huang, Marian Caikovski, Shaoquan Ji, Amanda McGrath, Myra G. Custorio, Chad J. Creighton, Paul Maliakkal, Ekaterina Bogoslovskaia, Zhijun Du, Xiaomei Zhang, Michael T. Lewis, Fred Sablitzky, Cathrin Brisken, Yi Li
Journal:
Development
Development (2011) 138 (23): 5247–5256.
Published: 1 December 2011
.... 3 10 2011 © 2011. ID4 p38MAPK (MAPK14, MAPK11) Mammary development Breast cancer Wnt Mouse The ID (inhibitor of DNA binding) group of proteins comprises four members in vertebrates (ID1-4) that belong to the basic helix-loop-helix (bHLH) family of transcription...
Includes: Supplementary data
Journal Articles
FOXA1 is an essential determinant of ERα expression and mammary ductal morphogenesis
Available to PurchaseGina M. Bernardo, Kristen L. Lozada, John D. Miedler, Gwyndolen Harburg, Sylvia C. Hewitt, Jonathan D. Mosley, Andrew K. Godwin, Kenneth S. Korach, Jane E. Visvader, Klaus H. Kaestner, Fadi W. Abdul-Karim, Monica M. Montano, Ruth A. Keri
Journal:
Development
Development (2010) 137 (12): 2045–2054.
Published: 15 June 2010
... predict favorable outcome in breast cancer patients, and their expression correlates with a differentiated, luminal tumor subtype. As transcription factors, each functions in the morphogenesis of various organs, with ERα and GATA3 being established regulators of mammary gland development. Interdependency...
Includes: Supplementary data
Journal Articles
Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1
Available to PurchaseMichael T. Lewis, Sarajane Ross, Phyllis A. Strickland, Charles W. Sugnet, Elsa Jimenez, Matthew P. Scott, Charles W. Daniel
Journal:
Development
Development (1999) 126 (22): 5181–5193.
Published: 15 November 1999
... and Biophysics, University of Colorado School of Medicine, Box C240, Room 3802, Denver, CO 80262, USA 30 08 1999 21 10 1999 © 1999 by Company of Biologists 1999 Hedgehog signal transduction Organogenesis Breast cancer Mammary gland Mouse Mammary gland development ( Fig. 1...
