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Keywords: Brain damage
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Journal Articles

The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and dengue virus

In collection:
Neural development
Qiang Shao, Stephanie Herrlinger, Ya-Nan Zhu, Mei Yang, Forrest Goodfellow, Steven L. Stice, Xiao-Peng Qi, Melinda A. Brindley, Jian-Fu Chen
Journal: Development
Development (2017) 144 (22): 4114–4124.
https://doi.org/10.1242/dev.156752
Published: 15 November 2017
... with the currently circulating Asian lineage of ZIKV (MEX1-44), DENV2 grows slower, causes less neuronal death and fails to cause postnatal animal death. Surprisingly, our side-by-side comparison uncovered that the African ZIKV isolate (MR-766) is more potent at causing brain damage and postnatal lethality than MEX1...
View article titled, The African Zika virus MR-766 is more virulent and causes more severe <span class="search-highlight">brain</span> <span class="search-highlight">damage</span> than current Asian lineage and dengue virus
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Includes: Supplementary data