... domain but limited the size of the sensory domain by influencing their adjoining boundary position via Jag1 regulation during development. Mybl2 loss-of-function simultaneously decreased proliferation in the inner sulcus and increased the size of the sensory domain, resulting in a wider sensory...

...Wesley R. Neher; Carolyn G. Rasmussen; Siobhan A. Braybrook; Vladimir Lažetić; Claire E. Stowers; Paul T. Mooney; Anne W. Sylvester; Patricia S. Springer ABSTRACT The maize ligule is an epidermis-derived structure that arises from the preligule band (PLB) at a boundary between the blade and sheath...

...Navid Nouri; Rajeshwar Awatramani The mesodiencephalic floor plate (mdFP) is the source of diverse neuron types. Yet, how this structure is compartmentalized has not been clearly elucidated. Here, we identify a novel boundary subdividing the mdFP into two microdomains, defined by engrailed 1 ( En1...

...-LexGAD/Gal4 generates tissues composed of clones that express either Gal4 or LexGAD, thus allowing the study of interactions between different types of genetically manipulated cells. By combining CoinFLP-LexGAD/Gal4 with the split-GFP system GRASP, boundaries between genetically distinct cell populations...

... signals. Communication between the meristem and lateral organs is crucial for meristem maintenance and organ patterning, and organ boundaries are thought to be important for mediating this communication. Arabidopsis thaliana LATERAL ORGAN FUSION1 ( LOF1 ) encodes a MYB-domain transcription factor...

... factor expressed in narrow stripes at the leaf margins, flanking the distal side of future leaflet primordia, and at the boundaries between the SAM and leaf primordia. Leaf-specific overexpression of the microRNA miR164 , a negative regulator of GOB -like genes,also leads to loss of secondary-leaflet...

... overlap between the prospective autopod and zeugopod in the distal limb bud at an early stage (stage 19), whereas a limb bud at this stage has already regionalized the proximal compartments for the prospective stylopod and zeugopod. A clearer boundary of cell fate specifying the prospective autopod...

...Robert J. Major; Kenneth D. Irvine Compartment boundaries play key roles in tissue organization by separating cell populations. Activation of the Notch receptor is required for dorsoventral (DV) compartmentalization of the Drosophila wing, but the nature of its requirement has been controversial...

...Marc Amoyel; Yi-Chuan Cheng; Yun-Jin Jiang; David G. Wilkinson The formation of localised signalling centres is essential for patterning of a number of tissues during development. Previous work has revealed that a distinct population of boundary cells forms at the interface of segments...

...Susan E. Schweinsberg; Paul Schedl The Fab-7 boundary functions to ensure the autonomous activity of the iab-6 and iab-7 cis-regulatory domains in the Drosophila Bithorax Complex from early embryogenesis through to the adult stage. Although Fab-7 is required only for the proper development...

...Patrick Laufs; Alexis Peaucelle; Halima Morin; Jan Traas We have analysed the role of a microRNA, miR164 , in boundary formation during organ initiation from Arabidopsis meristems. The establishment and maintenance of the boundary domain are controlled by three partially redundant genes, CUP-SHAPED...

...Virginie Lecaudey; Isabelle Anselme; Frédéric Rosa; Sylvie Schneider-Maunoury Early brain regionalisation involves the activation of genes coding for transcription factors in distinct domains of the neural plate. The limits of these domains often prefigure morphological boundaries...

...Florence Janody; Zara Martirosyan; Aude Benlali; Jessica E. Treisman The organizing centers for Drosophila imaginal disc development are created at straight boundaries between compartments; these are maintained by differences in cell affinity controlled by selector genes and intercellular signals...

...Ilham Hogga; François Karch The Fab-7 chromatin domain boundary insures functional autonomy of the iab-6 and iab-7 cis -regulatory domains in the bithorax complex (BX-C). We have previously shown that chromatin insulators such as gypsy or scs min are potent insulators that cannot substitute...

... ) which, in turn, negatively regulates other knox genes including KNAT1 and KNAT2, and positively regulates the novel gene LATERAL ORGAN BOUNDARIES ( LOB ). Genetic interactions with a second gene, ASYMMETRIC LEAVES2 ( AS2 ), indicate it acts at the same position in this hierarchy as AS1 . We have used...

... . Although there are differences, the wingless/Wnt- expressing cells and en -expressing cells seem to define an important boundary that is conserved among arthropods. This boundary may match the parasegmental compartment boundary and is even visible morphologically in the spider embryo. An additional piece...

... neuron populations extend axons across the ventral midline and through the ventral white matter along an arcuate trajectory on the contralateral side of the floor plate. Within the dorsal (chick) and intermediate (mouse) marginal zone, commissural axons turn at a conserved boundary of transmembrane...

... expression is subsequently absent from the nascent Rathke’s pouch as soon as it becomes morphologically visible, creating a Shh boundary within the oral epithelium. We used oral ectoderm/Rathke’s pouch-specific 5′ regulatory sequences ( Pitx1 HS ) from the bicoid related pituitary homeobox gene ( Pitx1...

... in the developing telencephalon, the cerebral cortex and the ganglionic eminence (the prospective basal ganglia). The analysis in wild-type mice confirmed that the cortico-striatal boundary acts as a semipermeable filter and allows a proportion of cells from the ganglionic eminence to invade the cortex...

...Carol Irving; Ivor Mason ABSTRACT The midbrain-hindbrain boundary, or isthmus, is the source of signals that are responsible for regional specification of both the midbrain and anterior hindbrain. Fibroblast growth factor 8 (Fgf8) is expressed specifically at the isthmus and there is now good...