... attributable to failed differentiation or loss of non-skeletal neural crest derivatives. We report here an additional, previously undescribed requirement for Sox10 in bone mineralization. Neither crest- nor mesoderm-derived bones initiate mineralization on time in zebrafish sox10 mutants, despite normal...

... limb bud mesenchymal progenitors slows chondrocyte differentiation affecting formation of hypertrophic chondrocytes and the primary ossification center. Endochondral ossification Bone mineralization Chondrocyte hypertrophy Phex Natural Sciences and Engineering Research Council...