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Keywords: Bmp2
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Journal Articles
Journal: Development
Development (2022) 149 (14): dev200633.
Published: 14 July 2022
... represses low density lipoprotein receptor-related protein 2 ( Lrp2 ), which has been shown to restrict eye overgrowth. Bone morphogenetic protein 2 (BMP2) is the downstream effector of Srebp2 and Lrp2 , and Bmp2 is suppressed by SREBP2 transcriptionally but activated by Lrp2 . During postnatal development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (13): dev163378.
Published: 2 July 2018
... Bmp2 expression in the mouse chamber myocardium changes the transcriptional signature of adjacent chamber endocardial cells into valve tissue, and enables them to undergo epithelial-mesenchyme transition. This induction is independent of valve myocardium specification and requires high levels of Notch1...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (13): 2398–2409.
Published: 1 July 2016
... and impaired astrocytic proliferation and, consequently, death of neocortical neurons. Mechanistically, YAP was activated by BMP2, and the active/nuclear YAP was crucial for BMP2 induction and stabilization of SMAD1 and astrocytic differentiation. Expression of SMAD1 in YAP-deficient NSCs partially rescued...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (4): 551–559.
Published: 15 February 2010
... this endogenous regeneration model in neonatal mice, we have found that noggin treatment inhibits regeneration, thus suggesting a bone morphogenetic protein (BMP) requirement. Using non-regenerating amputation wounds, we show that BMP7 or BMP2 can induce a regenerative response. BMP-induced regeneration involves...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (22): 3775–3787.
Published: 15 November 2008
...: Department of Developmental and Cell Biology, UCI, Irvine,CA 92697, USA 1 10 2008 © 2008. 2008 Cyp26b1 Retinoic acid Bmp2 Cartilage Bone Chondrocyte Osteoblast Osteopontin Osterix Craniofacial development Vertebra Zebrafish Skeletal development is highly conserved...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (7): 1499–1509.
Published: 1 April 2005
...2005. 2005 Feather morphogenesis Quail-duck chimeras Neural crest transplants Epithelial-mesenchymal interactions Modularity Plasticity Evolutionary developmental biology bmp4 bmp2 shh delta Feathers are a defining feature of birds. They are essential for flight...
Journal Articles
Journal: Development
Development (2004) 131 (18): 4581–4592.
Published: 15 September 2004
... Bmp2 and Bmp7 expression in Hoxa13 mutant limbs. Biochemical analyses identified a novel series of Bmp2 and Bmp7 enhancer regions that directly interact with the HOXA13 DNA-binding domain and activate gene expression in the presence of HOXA13. Immunoprecipitation of HOXA13- Bmp2 and HOXA13- Bmp7...
Journal Articles
Journal: Development
Development (2004) 131 (17): 4201–4211.
Published: 1 September 2004
... crista that corresponds to the Bone morphogenetic protein 2 ( Bmp2 )-positive domain in the canal pouch. Using retroviruses or beads to increase Fibroblast Growth Factors (FGFs) for gain-of-function and beads soaked with the FGF inhibitor SU5402 for loss-of-function experiments,we show that FGFs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (21): 5203–5215.
Published: 1 November 2003
... ephrin A5 by a DNA binding-dependent mechanism, ephrin A2 by a DNA binding-independent mechanism, and CBF2, SOHo1, GH6 and EphA3 by dual mechanisms. BMP2 expression begins double-gradiently in the retina from E5 in a complementary pattern to Ventroptin expression. Ventroptin antagonizes BMP2 as well...
Journal Articles
Journal: Development
Development (2001) 128 (12): 2269–2279.
Published: 15 June 2001
... drawn in studies based on these maps. We present accurate fate maps of the heart-forming region (HFR) in avian embryos and show that the putative cardiogenic molecular markers Bmp2 and Nkx2.5 do not govern the boundaries of the HFR as suggested in the literature. Moreover, this paper presents the first...